EIF3I and PDC

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
BioGRID (two hybrid)

		EIF3I	PDC
Gene Name		eukaryotic translation initiation factor 3, subunit I	phosducin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Extracellular Vesicular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Cytosol
	Molecular Function	Translation Initiation Factor Activity Protein Binding	Phospholipase Inhibitor Activity
	Biological Process	Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process	G-protein Coupled Receptor Signaling Pathway Visual Perception Phototransduction Negative Regulation Of Catalytic Activity
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: EIF3A EIF3B EIF4G1 ESR1 ESR2 ESRRA ESRRG EXOSC6 HARS HNF4G LAMB1 LAMC1 LIG4 NR1H3 NR1I2 NR1I3 NR3C2 PAXIP1 PDC PDCL PPARD PSMC4 RARB RARG RORA RORB RORC SUMO4 TGFB1 TGFBR2 THRB TNNI1 VDR VIM	7 interactors: ADRBK1 CAMK2A CRX EIF3I PRKACA PSMC5 YWHAZ
Entrez ID		8668	5132
HPRD ID		04884	01373
Ensembl ID		ENSG00000084623	ENSG00000116703
Uniprot IDs		Q13347 Q5U0F4	P20941 Q52LP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Intracellular Receptor Signaling Pathway Response To Steroid Hormone Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Cellular Response To Hormone Stimulus Response To Hormone Response To Lipid Response To Organic Cyclic Compound Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Response To Organic Substance Macromolecule Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated Signal Transduction Biosynthetic Process RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Signaling Response To Stimulus Connective Tissue Development Cell Communication Organ Development Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Stimulus Nitrogen Compound Metabolic Process System Development Regulation Of Metabolic Process Negative Regulation Of Gene Expression Multicellular Organismal Development Negative Regulation Of Transcription, DNA-templated	Peptidyl-serine Phosphorylation Positive Regulation Of Transport Regulation Of The Force Of Heart Contraction Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Peptidyl-threonine Phosphorylation Apoptotic Process Activation Of Phospholipase C Activity Programmed Cell Death Regulation Of Cellular Localization Immune System Process Positive Regulation Of Phospholipase C Activity Cell Death Death Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Phospholipase Activity Immune Response Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Positive Regulation Of Lipase Activity Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of Photoreceptor Cell Differentiation Defense Response Regulation Of Cell Cycle Arrest Regulation Of Apoptotic Process Regulation Of Cell Death Histone H3-T6 Phosphorylation Regulation Of Secretion Regulation Of Signaling Mitotic Cell Cycle Process Mitochondrial Transport Regulation Of Muscle Contraction G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Response To Stress Gene Expression Phosphorylation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Inclusion Body Assembly Golgi Reassembly Innate Immune Response Cellular Response To Fibroblast Growth Factor Stimulus Intrinsic Apoptotic Signaling Pathway Regulation Of Calcium Ion Transport Response To Fibroblast Growth Factor
Tagcloud ?		advantages akt array chaperone clinicopathological clu clusterin complexing confers correlations ectopic eukaryotic facilitates forced hcc hepatocellular inhibiting metalloproteinase metastasis mmp13 ogx option proliferative promoted shorter silencing suppressing turn utilized	ascorbate aspartate concerns dicarboxylic dopamine dopaminergic excitotoxicity extracellular glutamate microdialysis mm mpp neurone neurotoxic neurotoxicity output perfused perfusion perfusions phenyl phenylpyridinium protected protective pyrrolidine separated striatal terminals tetrahydropyridine uptake
Tagcloud (Difference) ?		advantages akt array chaperone clinicopathological clu clusterin complexing confers correlations ectopic eukaryotic facilitates forced hcc hepatocellular inhibiting metalloproteinase metastasis mmp13 ogx option proliferative promoted shorter silencing suppressing turn utilized	ascorbate aspartate concerns dicarboxylic dopamine dopaminergic excitotoxicity extracellular glutamate microdialysis mm mpp neurone neurotoxic neurotoxicity output perfused perfusion perfusions phenyl phenylpyridinium protected protective pyrrolidine separated striatal terminals tetrahydropyridine uptake
Tagcloud (Intersection) ?