KIF17 and MAP3K11

Number of citations of the paper that reports this interaction (PMID 9427749)
54

Data Source:
BioGRID (two hybrid)

		KIF17	MAP3K11
Gene Name		kinesin family member 17	mitogen-activated protein kinase kinase kinase 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Primary Cilium Periciliary Membrane Compartment	Cytoplasm Centrosome Microtubule Membrane
	Molecular Function	ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Homodimerization Activity Rac GTPase Binding
	Biological Process	Organelle Organization Microtubule-based Movement Metabolic Process Protein Transport Vesicle-mediated Transport Neurogenesis Cell Projection Organization Protein Complex Localization	Activation Of MAPK Activity Protein Phosphorylation Microtubule-based Process JNK Cascade Activation Of JNKK Activity Activation Of JUN Kinase Activity Cell Death Cell Proliferation Peptidyl-tyrosine Phosphorylation Positive Regulation Of JUN Kinase Activity Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of JNK Cascade Protein Autophosphorylation
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APBA1 C16orf70 FHL5 GFI1B MAP3K10 MAP3K11 XPO1	27 interactors: AKT1 APP CDC42 CHUK CLEC4G COPS5 EPS8 IKBKB KIF17 KIF3A KIF3B KIFAP3 MAP2K4 MAP2K7 MAP3K12 MAP4K1 MAP4K2 MAPK8IP1 MAPK8IP2 MAPK8IP3 PIN1 RAC1 RHOG SH3RF1 STUB1 TRAF6 UBC
Entrez ID		57576	4296
HPRD ID		10388	02502
Ensembl ID		ENSG00000117245	ENSG00000173327
Uniprot IDs		Q9P2E2	Q16584
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of JNKK Activity Activation Of JUN Kinase Activity Activation Of MAPKK Activity Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of JNK Cascade Ribosomal Small Subunit Export From Nucleus Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Metabolic Process Gamma-aminobutyric Acid Secretion Regulation Of Metabolic Process Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity MAPK Cascade Negative Regulation Of Transcription, DNA-templated Ribosomal Large Subunit Export From Nucleus Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Activation Of Protein Kinase Activity Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Ribosomal Subunit Export From Nucleus Gamma-aminobutyric Acid Transport Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Regulation Of Histone H3-K4 Methylation Positive Regulation Of Kinase Activity Glutamate Secretion Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transferase Activity Protein Export From Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Centrosome Duplication Positive Regulation Of Cell Death	Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade JNK Cascade Regulation Of MAPK Cascade Regulation Of Signal Transduction Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Transferase Activity Regulation Of Intracellular Signal Transduction Regulation Of Signaling Regulation Of Phosphorylation Response To Stress Regulation Of Phosphorus Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Kinase Activity MAPK Cascade Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Regulation Of JUN Kinase Activity Fc Receptor Signaling Pathway Innate Immune Response Positive Regulation Of MAPK Cascade Signal Transduction Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Metabolic Process Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Protein Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Immune System Process Toll-like Receptor 2 Signaling Pathway Positive Regulation Of JNK Cascade Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?		calmodulin camk cargo compartments complexity confinement conversely dendrites dendritic distances dramatically exits kinesin locally mobile nascent processed regimes restricts scales secretory segments spatial spatially tight trafficking transported tuned zones	acceleration activate agar besides carcinogenesis cdk2 colony crkl cycle cycling1 facilitate g1 htert mb mda methylate methyltransferase mynd oncogenes phenotypes pik3cb riz set smyd3 soft stat1 transduction transformed wnt10b
Tagcloud (Difference) ?		calmodulin camk cargo compartments complexity confinement conversely dendrites dendritic distances dramatically exits kinesin locally mobile nascent processed regimes restricts scales secretory segments spatial spatially tight trafficking transported tuned zones	acceleration activate agar besides carcinogenesis cdk2 colony crkl cycle cycling1 facilitate g1 htert mb mda methylate methyltransferase mynd oncogenes phenotypes pik3cb riz set smyd3 soft stat1 transduction transformed wnt10b
Tagcloud (Intersection) ?