FAM83D and DYNC1I1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FAM83D	DYNC1I1
Gene Name		family with sequence similarity 83, member D	dynein, cytoplasmic 1, intermediate chain 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function		Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding
	Biological Process	Mitotic Nuclear Division Cell Division	Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule
Pathways			MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS			Immune reponse to smallpox (secreted IL-10) ( 22610502) Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: CSNK1E DYNC1I1 GADD45A GSK3B PRMT1	31 interactors: ANXA7 BICD1 C2orf44 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NUDT21 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 UBC
Entrez ID		81610	1780
HPRD ID		12744	04798
Ensembl ID		ENSG00000101447	ENSG00000158560
Uniprot IDs		Q9H4H8	A4D1I7 B4DME3 F5H050 G5E9K1 O14576 Q8N542 Q8TBF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Mechanical Stimulus Peptidyl-serine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Positive Regulation Of Wnt Signaling Pathway Circadian Rhythm Peptidyl-amino Acid Modification Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Cell Cycle Process Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase Activity Positive Regulation Of Protein Catabolic Process Response To Mechanical Stimulus Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Cellular Response To Interleukin-3 Positive Regulation Of Protein Metabolic Process Wnt Signaling Pathway Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Proteolysis Protein Localization To Microtubule Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Rhythmic Process Cell Cycle Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Negative Regulation Of Dendrite Morphogenesis Negative Regulation Of Protein Phosphorylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy	Regulation Of Cellular Component Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intracellular MRNA Localization Positive Regulation Of Cell Death Regulation Of Organelle Organization Regulation Of Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Mitochondrion Organization Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Tetramerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Processing And Presentation Regulation Of Ras GTPase Activity Viral Process Mitotic Nuclear Division Intracellular Transport Of Virus Response To Metal Ion Positive Regulation Of Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Intracellular Signal Transduction DNA Damage Checkpoint Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway Programmed Cell Death Ribonucleoprotein Complex Assembly Negative Regulation Of Phosphorylation
Tagcloud ?			10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated
Tagcloud (Difference) ?			10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated
Tagcloud (Intersection) ?