DYNC1I1 and STAU1

Number of citations of the paper that reports this interaction (PMID 15121898)
40

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		DYNC1I1	STAU1
Gene Name		dynein, cytoplasmic 1, intermediate chain 1	staufen double-stranded RNA binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Microtubule Associated Complex Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Vesicular Exosome
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding	Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding Poly(A) RNA Binding
	Biological Process	Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule	Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-10) ( 22610502) Obesity-related traits ( 23251661)
Protein-Protein Interactions		31 interactors: ANXA7 BICD1 C2orf44 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NUDT21 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 UBC	39 interactors: APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NXT1 PABPC1 PABPN1 PPP1CA PPP1CC RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 TAX1BP3 TUBB TUBB4A UBE2D3 UPF1 ZMAT3
Entrez ID		1780	6780
HPRD ID		04798	03422
Ensembl ID		ENSG00000158560	ENSG00000124214
Uniprot IDs		A4D1I7 B4DME3 F5H050 G5E9K1 O14576 Q8N542 Q8TBF7	B3KRE0 O95793 Q6PJX3
PDB IDs			4DKK
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intracellular MRNA Localization Positive Regulation Of Cell Death Regulation Of Organelle Organization Regulation Of Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Mitochondrion Organization Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Tetramerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Processing And Presentation Regulation Of Ras GTPase Activity Viral Process Mitotic Nuclear Division Intracellular Transport Of Virus Response To Metal Ion Positive Regulation Of Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Intracellular Signal Transduction DNA Damage Checkpoint Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway Programmed Cell Death Ribonucleoprotein Complex Assembly Negative Regulation Of Phosphorylation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Intracellular Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Localization RNA Transport Cytoskeleton-dependent Intracellular Transport RNA Localization Viral Process Establishment Of Localization In Cell MRNA Processing Viral Transcription SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Protein Complex Disassembly Cotranslational Protein Targeting To Membrane Protein Targeting To ER Viral Life Cycle Neuron Projection Morphogenesis Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Catabolic Process Protein Complex Disassembly RNA Splicing Cytoplasmic Transport MRNA Transport Axonogenesis Organelle Transport Along Microtubule Protein Localization To Endoplasmic Reticulum Translational Initiation Microtubule-based Transport Movement Of Cell Or Subcellular Component Microtubule-based Process Axon Development RNA Processing Translational Termination Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of Translation Cell Projection Morphogenesis Protein Targeting To Membrane RNA Export From Nucleus Cell Part Morphogenesis Translational Elongation MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Microtubule-based Movement Developmental Cell Growth
Tagcloud ?		10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated	activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Difference) ?		10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated	activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Intersection) ?