DYNC1I1 and C2orf44

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DYNC1I1	C2orf44
Gene Name		dynein, cytoplasmic 1, intermediate chain 1	chromosome 2 open reading frame 44
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding	Kinase Binding
	Biological Process	Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule	Protein Oligomerization
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-10) ( 22610502) Obesity-related traits ( 23251661)
Protein-Protein Interactions		31 interactors: ANXA7 BICD1 C2orf44 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NUDT21 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 UBC	12 interactors: CSNK1E CSNK1G1 CSNK1G2 DYNC1I1 HCK MED31 PDPK1 PRKAR1A RAB35 RPS27 TAB1 TNNT1
Entrez ID		1780	80304
HPRD ID		04798	07972
Ensembl ID		ENSG00000158560	ENSG00000163026
Uniprot IDs		A4D1I7 B4DME3 F5H050 G5E9K1 O14576 Q8N542 Q8TBF7	Q9H6R7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intracellular MRNA Localization Positive Regulation Of Cell Death Regulation Of Organelle Organization Regulation Of Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Mitochondrion Organization Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Tetramerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Processing And Presentation Regulation Of Ras GTPase Activity Viral Process Mitotic Nuclear Division Intracellular Transport Of Virus Response To Metal Ion Positive Regulation Of Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Intracellular Signal Transduction DNA Damage Checkpoint Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway Programmed Cell Death Ribonucleoprotein Complex Assembly Negative Regulation Of Phosphorylation	Regulation Of Cell Shape Peptidyl-serine Phosphorylation Peptidyl-amino Acid Modification Regulation Of Cell Morphogenesis Phosphorylation Cellular Response To Growth Factor Stimulus Protein Autophosphorylation Regulation Of Cellular Component Organization Response To Growth Factor Endocytosis Protein Phosphorylation Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Immune System Process Wnt Signaling Pathway Vesicle-mediated Transport Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Innate Immune Response Respiratory Burst After Phagocytosis Positive Regulation Of Phospholipase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transport Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Leukocyte Migration Involved In Immune Response Signal Transduction Response To Peptide Hormone Immune Response-regulating Signaling Pathway Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Kinase Activity Cellular Response To Organic Substance Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Signaling Innate Immune Response-activating Signal Transduction Cell Communication Mesoderm Development Activation Of Innate Immune Response Positive Regulation Of Transferase Activity Respiratory Burst Involved In Defense Response Positive Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Cellular Response To Hormone Stimulus Immune Response
Tagcloud ?		10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated
Tagcloud (Difference) ?		10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated
Tagcloud (Intersection) ?