DYNC1I1 and KAT7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DYNC1I1	KAT7
Gene Name		dynein, cytoplasmic 1, intermediate chain 1	K(lysine) acetyltransferase 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		MHC class II antigen presentation Adaptive Immune System	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-10) ( 22610502) Obesity-related traits ( 23251661)
Protein-Protein Interactions		31 interactors: ANXA7 BICD1 C2orf44 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NUDT21 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 UBC	43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165
Entrez ID		1780	11143
HPRD ID		04798	07135
Ensembl ID		ENSG00000158560	ENSG00000136504
Uniprot IDs		A4D1I7 B4DME3 F5H050 G5E9K1 O14576 Q8N542 Q8TBF7	O95251
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intracellular MRNA Localization Positive Regulation Of Cell Death Regulation Of Organelle Organization Regulation Of Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Mitochondrion Organization Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Tetramerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Processing And Presentation Regulation Of Ras GTPase Activity Viral Process Mitotic Nuclear Division Intracellular Transport Of Virus Response To Metal Ion Positive Regulation Of Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Intracellular Signal Transduction DNA Damage Checkpoint Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway Programmed Cell Death Ribonucleoprotein Complex Assembly Negative Regulation Of Phosphorylation	Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport
Tagcloud ?		10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated	acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Difference) ?		10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated	acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Intersection) ?