TRPC1 and MX1

Number of citations of the paper that reports this interaction (PMID 15757897)
7

Data Source:
HPRD (in vitro, in vivo)

		TRPC1	MX1
Gene Name		transient receptor potential cation channel, subfamily C, member 1	MX dynamin-like GTPase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Sarcomere Costamere Receptor Complex Membrane Raft	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Cation Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Ion Channel Binding Inositol 1,4,5 Trisphosphate Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Calcium Ion Transport Axon Guidance Ion Transmembrane Transport Saliva Secretion Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cytosolic Calcium Ion Homeostasis Response To Calcium Ion Transmembrane Transport Calcium Ion Transmembrane Transport	Apoptotic Process Defense Response Signal Transduction Metabolic Process Response To Virus Cytokine-mediated Signaling Pathway Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Signaling by the B Cell Receptor (BCR) Ion channel transport Axon guidance Role of second messengers in netrin-1 signaling TRP channels Stimuli-sensing channels Netrin-1 signaling Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System	ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: BMPR2 CAV1 GRIA1 HOMER1 HOMER3 ITPR2 ITPR3 MDFI MX1 PKD2 RHOA TRPC3 TRPC4 TRPC5	17 interactors: ACTB APP BLM CAB39L DAXX FANCA PIAS1 SIAH1 SP100 SUMO1 TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBB
Entrez ID		7220	4599
HPRD ID		11894	00919
Ensembl ID		ENSG00000144935	ENSG00000157601
Uniprot IDs		P48995	P20591
PDB IDs			3LJB 3SZR 3ZYS
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transport Metal Ion Transport Positive Regulation Of Calcium Ion Transport Response To Stimulus Response To Calcium Ion Regulation Of Cellular Localization Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signaling Cation Transport Ion Transport Cell Communication Response To External Stimulus Blood Coagulation Hemostasis Regulation Of Intracellular Transport Ion Transmembrane Transport Platelet Activation Positive Regulation Of Ion Transport Response To Inorganic Substance Glutamate Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cation Transmembrane Transport Cellular Response To Stimulus Regulation Of Signaling Regulation Of Cation Channel Activity Regulation Of Body Fluid Levels Regulation Of Endothelial Cell Proliferation Wound Healing Regulation Of Transcription Factor Import Into Nucleus Anatomical Structure Morphogenesis Regulation Of Ion Transport Regulation Of Protein Transport Transmembrane Transport Response To Organic Substance Response To Stress Regulation Of Establishment Of Protein Localization Response To Metal Ion Response To Wounding Intracellular Signal Transduction Positive Regulation Of Transport Positive Regulation Of Signal Transduction Inositol Phosphate-mediated Signaling Regulation Of Store-operated Calcium Entry G-protein Coupled Glutamate Receptor Signaling Pathway Axon Guidance	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Calcium Ion Transmembrane Transport Neuron Development Cell Morphogenesis Movement Of Cell Or Subcellular Component Response To Stimulus Neuron Differentiation Cell Projection Organization Calcium Ion Transport Locomotion Platelet Activation Response To Stress Generation Of Neurons Neurogenesis Cell Development Response To External Stimulus Regulation Of Body Fluid Levels Cell Activation Nervous System Development Blood Coagulation Hemostasis Intracellular Receptor Signaling Pathway Anatomical Structure Development Anatomical Structure Morphogenesis Innate Immune Response Metal Ion Transport System Development Cell Differentiation Cation Transmembrane Transport Regulation Of Binding Positive Regulation Of Calcium Ion Transport Developmental Process Wound Healing Multicellular Organismal Development Interferon-gamma-mediated Signaling Pathway Response To Wounding Cation Transport Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Cellular Response To Interferon-gamma Protein Sumoylation
Tagcloud ?		ca2 cation cdna channels converted dami details entry excitable hel homologues htrp1 identity influx meg01 megakaryocytes megakaryocytic platelets primers producers revealing sizes splicing store trpc2 trpl	antiproliferative apl appear autoantigen bodies contain disruption elucidation fusion harbors ifn ifns inactivation interferons labelled leukemogenesis link mediate mediator microspeckles nbs ndp52 pml promyelocytic rxrs sequestration sp100 speckles suppressing
Tagcloud (Difference) ?		ca2 cation cdna channels converted dami details entry excitable hel homologues htrp1 identity influx meg01 megakaryocytes megakaryocytic platelets primers producers revealing sizes splicing store trpc2 trpl	antiproliferative apl appear autoantigen bodies contain disruption elucidation fusion harbors ifn ifns inactivation interferons labelled leukemogenesis link mediate mediator microspeckles nbs ndp52 pml promyelocytic rxrs sequestration sp100 speckles suppressing
Tagcloud (Intersection) ?