MX1 and TRPC5

Number of citations of the paper that reports this interaction (PMID 15757897)
7

Data Source:
HPRD (in vivo, in vitro)

		MX1	TRPC5
Gene Name		MX dynamin-like GTPase 1	transient receptor potential cation channel, subfamily C, member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Calcium Channel Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Apoptotic Process Defense Response Signal Transduction Metabolic Process Response To Virus Cytokine-mediated Signaling Pathway Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon Signaling Pathway	Calcium Ion Transport Nervous System Development Axon Guidance Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Antiviral mechanism by IFN-stimulated genes	Ion channel transport Axon guidance Role of second messengers in netrin-1 signaling TRP channels Stimuli-sensing channels Netrin-1 signaling
Drugs
Diseases
GWAS			Smoking behavior ( 19247474)
Protein-Protein Interactions		17 interactors: ACTB APP BLM CAB39L DAXX FANCA PIAS1 SIAH1 SP100 SUMO1 TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBB	7 interactors: ITPR3 MX1 SLC9A3R1 STMN2 STMN3 TRPC1 TRPC4
Entrez ID		4599	7224
HPRD ID		00919	02273
Ensembl ID		ENSG00000157601	ENSG00000072315
Uniprot IDs		P20591	Q9UL62
PDB IDs		3LJB 3SZR 3ZYS
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Calcium Ion Transmembrane Transport Neuron Development Cell Morphogenesis Movement Of Cell Or Subcellular Component Response To Stimulus Neuron Differentiation Cell Projection Organization Calcium Ion Transport Locomotion Platelet Activation Response To Stress Generation Of Neurons Neurogenesis Cell Development Response To External Stimulus Regulation Of Body Fluid Levels Cell Activation Nervous System Development Blood Coagulation Hemostasis Intracellular Receptor Signaling Pathway Anatomical Structure Development Anatomical Structure Morphogenesis Innate Immune Response Metal Ion Transport System Development Cell Differentiation Cation Transmembrane Transport Regulation Of Binding Positive Regulation Of Calcium Ion Transport Developmental Process Wound Healing Multicellular Organismal Development Interferon-gamma-mediated Signaling Pathway Response To Wounding Cation Transport Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Cellular Response To Interferon-gamma Protein Sumoylation	Calcium Ion Transmembrane Transport Metal Ion Transport Calcium Ion Transport Acid Secretion Cell Projection Organization Cation Transport Regulation Of Microtubule Polymerization Or Depolymerization Cellular Ion Homeostasis Renal Phosphate Ion Absorption Cellular Chemical Homeostasis Ion Homeostasis Response To Calcium Ion Generation Of Neurons Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Secretion Monocarboxylic Acid Transport Neurogenesis Regulation Of Microtubule Cytoskeleton Organization Cellular Homeostasis Ion Transport Regulation Of Microtubule-based Process Gamma-aminobutyric Acid Secretion Cytosolic Calcium Ion Homeostasis Neuron Projection Development Renal Sodium Ion Transport Positive Regulation Of Microtubule Depolymerization Chemical Homeostasis Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Sensory Perception Of Sweet Taste Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Cation Transmembrane Transport Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Rac Protein Signal Transduction Sensory Perception Of Umami Taste Neuron Development Nervous System Development Phospholipase C-activating Dopamine Receptor Signaling Pathway Gamma-aminobutyric Acid Transport Saliva Secretion Bile Acid Secretion Microtubule Depolymerization Cellular Calcium Ion Homeostasis Neuron Differentiation Carboxylic Acid Transport Calcium Ion Homeostasis Organic Acid Transport Oligopeptide Transport Negative Regulation Of Sodium Ion Transport
Tagcloud ?		antiproliferative apl appear autoantigen bodies contain disruption elucidation fusion harbors ifn ifns inactivation interferons labelled leukemogenesis link mediate mediator microspeckles nbs ndp52 pml promyelocytic rxrs sequestration sp100 speckles suppressing	allosteric ankyrin arises belongs branched channels detectors enthalpy evolved gating kcal macroscopic melastatin polymodal specialized subfamilies tetramers thermal trpa trpa1 trpm trpm8 trpv trpv1 trpv3 vanilloid voltage
Tagcloud (Difference) ?		antiproliferative apl appear autoantigen bodies contain disruption elucidation fusion harbors ifn ifns inactivation interferons labelled leukemogenesis link mediate mediator microspeckles nbs ndp52 pml promyelocytic rxrs sequestration sp100 speckles suppressing	allosteric ankyrin arises belongs branched channels detectors enthalpy evolved gating kcal macroscopic melastatin polymodal specialized subfamilies tetramers thermal trpa trpa1 trpm trpm8 trpv trpv1 trpv3 vanilloid voltage
Tagcloud (Intersection) ?