TCP1 and PDCL

Number of citations of the paper that reports this interaction (PMID 12060742)
23

Data Source:
HPRD (in vitro)

		TCP1	PDCL
Gene Name		t-complex 1	phosducin-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Acrosomal Vesicle Zona Pellucida Receptor Complex Nuclear Heterochromatin Golgi Apparatus Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Unfolded Protein Binding	Receptor Signaling Protein Activity Protein Binding Protein Complex Binding
	Biological Process	Protein Folding Tubulin Complex Assembly Binding Of Sperm To Zona Pellucida Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Toxin Transport Regulation Of Macrophage Apoptotic Process	Protein Folding Signal Transduction Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Protein Refolding Heterotrimeric G-protein Complex Assembly
Pathways		Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: CBFA2T2 CCT5 CCT7 CDC20 FANCA HSPA8 PDCL SH3BP4 TUBA4A TUBA8 VRK2 YWHAQ	7 interactors: ADRBK1 CCT5 EIF3I GNB1 IKBKG PSMC5 TCP1
Entrez ID		6950	5082
HPRD ID		01748	05108
Ensembl ID		ENSG00000120438	ENSG00000136940
Uniprot IDs		E7EQR6 F5H282 P17987	Q13371
PDB IDs
Enriched GO Terms of Interacting Partners?		'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Protein Folding Toxin Transport Regulation Of Cellular Component Organization Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Negative Regulation Of Fibril Organization Heterotrimeric G-protein Complex Assembly Protein Polymerization Protein Complex Assembly Regulation Of Fibril Organization Regulation Of Interleukin-1-mediated Signaling Pathway Cell Recognition Single Fertilization Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Refolding Clathrin Coat Disassembly Fertilization Activation Of Anaphase-promoting Complex Activity Positive Regulation Of Synaptic Plasticity Vesicle-mediated Transport	G-protein Coupled Acetylcholine Receptor Signaling Pathway Toxin Transport Binding Of Sperm To Zona Pellucida Sperm-egg Recognition 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell-cell Recognition Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Cell Recognition Single Fertilization Fertilization Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Inclusion Body Assembly Cardiac Muscle Cell Apoptotic Process Apoptotic Process Negative Regulation Of Striated Muscle Contraction Muscle Cell Apoptotic Process Programmed Cell Death Response To Virus Regulation Of The Force Of Heart Contraction By Chemical Signal Cell Death Death Tachykinin Receptor Signaling Pathway Cellular Metabolic Process Negative Regulation Of Signal Transduction Protein Folding Cellular Protein Metabolic Process Positive Regulation Of Catecholamine Secretion Regulation Of Macrophage Apoptotic Process Negative Regulation Of Signaling Tubulin Complex Assembly Cellular Response To Prostaglandin E Stimulus Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Regulation Of Inclusion Body Assembly Regulation Of Signal Transduction Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway
Tagcloud ?		associates cct chaperonin combinatorial comprised concerning concordant constituting counting factorial fixed implies infer inter micro microcomplexes orientation partners possibilities predictions probable ring subsets subunit subunits symmetry topology torodial wts	2h2o 4h2o adp adriamycin anticancer antigrowth bax chemotherapeutics cisplatin complexes elucidate far fluorescein iodide isothiocyanate jurkat molt mtt palladium predominately propidium regarded ribose sac satisfactory terpy thp treating warranted
Tagcloud (Difference) ?		associates cct chaperonin combinatorial comprised concerning concordant constituting counting factorial fixed implies infer inter micro microcomplexes orientation partners possibilities predictions probable ring subsets subunit subunits symmetry topology torodial wts	2h2o 4h2o adp adriamycin anticancer antigrowth bax chemotherapeutics cisplatin complexes elucidate far fluorescein iodide isothiocyanate jurkat molt mtt palladium predominately propidium regarded ribose sac satisfactory terpy thp treating warranted
Tagcloud (Intersection) ?