PTGFRN and CD9

Number of citations of the paper that reports this interaction (PMID 11278880)
49

Data Source:
HPRD (in vitro, in vivo)

		PTGFRN	CD9
Gene Name		prostaglandin F2 receptor inhibitor	CD9 molecule
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Integral Component Of Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Integrin Binding Protein Binding
	Biological Process	Lipid Particle Organization	Platelet Degranulation Movement Of Cell Or Subcellular Component Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Brain Development Blood Coagulation Negative Regulation Of Cell Proliferation Pathogenesis Response To Water Deprivation Oligodendrocyte Development Platelet Activation Paranodal Junction Assembly Multicellular Organism Reproduction
Pathways			Uptake and actions of bacterial toxins Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Fertilization Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)	Mean platelet volume ( 22139419) Paclitaxel-induced neuropathy ( 23776197) Platelet counts ( 22139419)
Protein-Protein Interactions		5 interactors: CD151 CD63 CD81 CD82 CD9	22 interactors: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT PRKCA PTGFRN SERPINH1 TSPAN4 VKORC1
Entrez ID		5738	928
HPRD ID		03124	00880
Ensembl ID		ENSG00000134247	ENSG00000010278
Uniprot IDs		Q9P2B2	B4DK09 P21926
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Cell Activation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Platelet Activation Cell Junction Assembly Cell Adhesion Locomotion Receptor-mediated Virion Attachment To Host Cell Regulation Of Rubidium Ion Transport Response To Water Deprivation Movement Of Cell Or Subcellular Component Exocytosis Virion Attachment To Host Cell Endosome To Melanosome Transport Pigment Granule Maturation Adhesion Of Symbiont To Host Cellular Pigment Accumulation Positive Regulation Of Integrin-mediated Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Blood Coagulation Hemostasis Hemidesmosome Assembly Fusion Of Sperm To Egg Plasma Membrane Paranodal Junction Assembly Secretion By Cell Plasma Membrane Fusion Positive Regulation Of Receptor Internalization Regulation Of Body Fluid Levels Wound Healing Secretion Response To Wounding Myelin Assembly Regulation Of Receptor Internalization Cell Proliferation Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of B Cell Proliferation Viral Entry Into Host Cell Oligodendrocyte Development Cell Migration Entry Into Host Cell Cell Motility Cell-substrate Junction Assembly Regulation Of B Cell Proliferation Regulation Of Lipid Kinase Activity Cellular Pigmentation Developmental Pigmentation T Cell Proliferation Positive Regulation Of B Cell Activation Oligodendrocyte Differentiation	Wound Healing Blood Coagulation Hemostasis Response To Wounding Regulation Of Body Fluid Levels Response To Stress Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Adhesion Integrin-mediated Signaling Pathway Regulation Of Immune System Process Regulation Of Protein Metabolic Process Learning Or Memory Cognition Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Proliferation Cell Migration Cell Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Regulation Of Cell Migration Extracellular Matrix Organization Associative Learning Extracellular Structure Organization Locomotion Cell Motility Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Positive Regulation Of Epithelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Tissue Development Cell-substrate Adhesion Positive Regulation Of Endocytosis Leukocyte Migration Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Single-organism Behavior Mesodermal Cell Differentiation Movement Of Cell Or Subcellular Component Positive Regulation Of Cell-substrate Adhesion Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling
Tagcloud ?			accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Difference) ?			accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Intersection) ?