PTGFRN and CD81

Number of citations of the paper that reports this interaction (PMID 11278880)
49

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		PTGFRN	CD81
Gene Name		prostaglandin F2 receptor inhibitor	CD81 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Integral Component Of Membrane	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding MHC Class II Protein Complex Binding
	Biological Process	Lipid Particle Organization	Activation Of MAPK Activity Phosphatidylinositol Biosynthetic Process Protein Localization Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Phosphatidylinositol Metabolic Process Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Regulation Of Cell Motility
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		5 interactors: CD151 CD63 CD81 CD82 CD9	20 interactors: ADRB2 CD19 CD9 CSNK2B DLG5 HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT MYOC PTGFRN RBBP6 RNF128 SHC1 TSPAN4 VKORC1 ZBTB16
Entrez ID		5738	975
HPRD ID		03124	08924
Ensembl ID		ENSG00000134247	ENSG00000110651
Uniprot IDs		Q9P2B2	E9PJK1 P60033
PDB IDs			1G8Q 1IV5 2AVZ
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Cell Activation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Platelet Activation Cell Junction Assembly Cell Adhesion Locomotion Receptor-mediated Virion Attachment To Host Cell Regulation Of Rubidium Ion Transport Response To Water Deprivation Movement Of Cell Or Subcellular Component Exocytosis Virion Attachment To Host Cell Endosome To Melanosome Transport Pigment Granule Maturation Adhesion Of Symbiont To Host Cellular Pigment Accumulation Positive Regulation Of Integrin-mediated Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Blood Coagulation Hemostasis Hemidesmosome Assembly Fusion Of Sperm To Egg Plasma Membrane Paranodal Junction Assembly Secretion By Cell Plasma Membrane Fusion Positive Regulation Of Receptor Internalization Regulation Of Body Fluid Levels Wound Healing Secretion Response To Wounding Myelin Assembly Regulation Of Receptor Internalization Cell Proliferation Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of B Cell Proliferation Viral Entry Into Host Cell Oligodendrocyte Development Cell Migration Entry Into Host Cell Cell Motility Cell-substrate Junction Assembly Regulation Of B Cell Proliferation Regulation Of Lipid Kinase Activity Cellular Pigmentation Developmental Pigmentation T Cell Proliferation Positive Regulation Of B Cell Activation Oligodendrocyte Differentiation	Organ Development ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation System Development Regulation Of Immune Response Regulation Of Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Developmental Process Positive Regulation Of Ossification B Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Cell Motility Response To Stress Negative Regulation Of Cell Proliferation Regulation Of Locomotion Cell Activation Regulation Of Cellular Component Movement B Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Tissue Development Fibroblast Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of Signal Transduction Innate Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Ossification Stem Cell Division Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Single Organismal Cell-cell Adhesion Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Cell Differentiation Bone Development Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of FasL Biosynthetic Process Zonula Adherens Assembly ERBB2-ERBB3 Signaling Pathway Mast Cell Proliferation Lymphocyte Differentiation
Tagcloud ?			000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Difference) ?			000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Intersection) ?