CD9 and IGSF8

Number of citations of the paper that reports this interaction (PMID 11504738)
46

Data Source:
HPRD (in vivo)

		CD9	IGSF8
Gene Name		CD9 molecule	immunoglobulin superfamily, member 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Vesicle Extracellular Vesicular Exosome	Plasma Membrane Membrane Integral Component Of Membrane Axon Synapse Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Protein Binding	Protein Binding
	Biological Process	Platelet Degranulation Movement Of Cell Or Subcellular Component Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Brain Development Blood Coagulation Negative Regulation Of Cell Proliferation Pathogenesis Response To Water Deprivation Oligodendrocyte Development Platelet Activation Paranodal Junction Assembly Multicellular Organism Reproduction	Movement Of Cell Or Subcellular Component Single Fertilization Nervous System Development Skeletal Muscle Tissue Development Cell Proliferation Regulation Of Cell Motility
Pathways		Uptake and actions of bacterial toxins Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Fertilization Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419) Paclitaxel-induced neuropathy ( 23776197) Platelet counts ( 22139419)
Protein-Protein Interactions		22 interactors: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT PRKCA PTGFRN SERPINH1 TSPAN4 VKORC1	9 interactors: A2M CD81 CD82 CD9 KRTAP10-3 KRTAP10-4 KRTAP10-7 KRTAP10-8 KRTAP10-9
Entrez ID		928	93185
HPRD ID		00880	09438
Ensembl ID		ENSG00000010278	ENSG00000162729
Uniprot IDs		B4DK09 P21926	Q969P0
PDB IDs
Enriched GO Terms of Interacting Partners?		Wound Healing Blood Coagulation Hemostasis Response To Wounding Regulation Of Body Fluid Levels Response To Stress Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Adhesion Integrin-mediated Signaling Pathway Regulation Of Immune System Process Regulation Of Protein Metabolic Process Learning Or Memory Cognition Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Proliferation Cell Migration Cell Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Regulation Of Cell Migration Extracellular Matrix Organization Associative Learning Extracellular Structure Organization Locomotion Cell Motility Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Positive Regulation Of Epithelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Tissue Development Cell-substrate Adhesion Positive Regulation Of Endocytosis Leukocyte Migration Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Single-organism Behavior Mesodermal Cell Differentiation Movement Of Cell Or Subcellular Component Positive Regulation Of Cell-substrate Adhesion Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling	Platelet Degranulation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Platelet Activation Negative Regulation Of Complement Activation, Lectin Pathway Receptor-mediated Virion Attachment To Host Cell Exocytosis Response To Water Deprivation Virion Attachment To Host Cell Blood Coagulation Hemostasis Adhesion Of Symbiont To Host Secretion By Cell Regulation Of Body Fluid Levels Fusion Of Sperm To Egg Plasma Membrane Wound Healing Blood Coagulation, Intrinsic Pathway Paranodal Junction Assembly Negative Regulation Of Complement Activation Secretion Plasma Membrane Fusion Cell Activation Response To Wounding Myelin Assembly Regulation Of Immune Response Regulation Of Complement Activation Negative Regulation Of Innate Immune Response Positive Regulation Of B Cell Proliferation Viral Entry Into Host Cell Oligodendrocyte Development Entry Into Host Cell Regulation Of Humoral Immune Response Regulation Of B Cell Proliferation Regulation Of Lipid Kinase Activity Regulation Of Immune System Process Regulation Of Acute Inflammatory Response Positive Regulation Of B Cell Activation Oligodendrocyte Differentiation Vesicle-mediated Transport Regulation Of Cell Proliferation Extracellular Matrix Disassembly Glial Cell Development Interaction With Host
Tagcloud ?		accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Difference) ?		accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Intersection) ?