FAM20C and PFDN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FAM20C	PFDN1
Gene Name		family with sequence similarity 20, member C	prefoldin subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Golgi Apparatus Extracellular Vesicular Exosome	Prefoldin Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Calcium Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding
	Biological Process	Protein Phosphorylation Positive Regulation Of Bone Mineralization Osteoclast Maturation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Osteoblast Differentiation Regulation Of Phosphorus Metabolic Process Enamel Mineralization Odontoblast Differentiation Dentinogenesis	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways			Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: FAM118B PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1	54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235
Entrez ID		56975	5201
HPRD ID		13298	05357
Ensembl ID			ENSG00000113068
Uniprot IDs		Q8IXL6	O60925
PDB IDs
Enriched GO Terms of Interacting Partners?		Fetal Process Involved In Parturition Skeletal Muscle Cell Proliferation Histone H3-K9 Dimethylation Nucleobase-containing Compound Metabolic Process Thymidine Metabolic Process Response To Cortisol Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Histone H3-K9 Trimethylation Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Peptidyl-lysine Dimethylation Nitrogen Compound Metabolic Process RNA Metabolic Process Chromatin Silencing At RDNA Parturition Negative Regulation Of Circadian Rhythm Gene Expression Histone H3-K9 Methylation Response To Copper Ion Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Peptidyl-lysine Trimethylation Termination Of RNA Polymerase I Transcription Macromolecule Biosynthetic Process Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Histone H3-K9 Modification Chromatin Silencing Pyrimidine Nucleobase Metabolic Process Spliceosomal SnRNP Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Regulation Of RNA Metabolic Process	Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis
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