PFDN1 and ALB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PFDN1	ALB
Gene Name		prefoldin subunit 1	albumin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Prefoldin Complex	Extracellular Region Basement Membrane Extracellular Space Nucleus Platelet Alpha Granule Lumen Protein Complex Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding	DNA Binding Fatty Acid Binding Copper Ion Binding Protein Binding Drug Binding Zinc Ion Binding Toxic Substance Binding Antioxidant Activity Oxygen Binding Enzyme Binding Pyridoxal Phosphate Binding Chaperone Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding	Retina Homeostasis Platelet Degranulation Transport Receptor-mediated Endocytosis Response To Nutrient Blood Coagulation Bile Acid Metabolic Process Cellular Response To Starvation Response To Organic Substance Bile Acid And Bile Salt Transport Hemolysis By Symbiont Of Host Erythrocytes Platelet Activation Lipoprotein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Sodium-independent Organic Anion Transport Small Molecule Metabolic Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Mercury Ion Maintenance Of Mitochondrion Location Transmembrane Transport Response To Platinum Ion
Pathways		Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding	Lipoprotein metabolism Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Recycling of bile acids and salts Platelet degranulation Lipid digestion, mobilization, and transport Transport of organic anions SLC-mediated transmembrane transport HDL-mediated lipid transport Scavenging of heme from plasma Response to elevated platelet cytosolic Ca2+ Platelet activation, signaling and aggregation Transport of vitamins, nucleosides, and related molecules
Drugs
Diseases
GWAS			Lipid metabolism phenotypes ( 22286219) Prostate cancer ( 23535732)
Protein-Protein Interactions		54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235	24 interactors: AGA AMBP APOE APP CRYAA CUBN F7 FCGRT HNF1A IMMT KLK3 LRP2 LUC7L2 NR5A2 ORM1 PFDN1 PON1 PRB3 RBP4 RYR2 SRGN ST13 TK1 YWHAG
Entrez ID		5201	213
HPRD ID		05357	00062
Ensembl ID		ENSG00000113068	ENSG00000163631
Uniprot IDs		O60925	C9JKR2 P02768
PDB IDs			1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2VDB 2VUE 2VUF 2XSI 2XVQ 2XVU 2XVV 2XVW 2XW0 2XW1 2YDF 3A73 3B9L 3B9M 3CX9 3JQZ 3JRY 3LU6 3LU7 3LU8 3SQJ 3TDL 3UIV 4E99 4EMX 4G03 4G04 4HGK 4HGM 4IW1 4IW2 4K2C 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis	Alcohol Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Sterol Metabolic Process Chemical Homeostasis Lipid Metabolic Process Homeostatic Process Response To External Stimulus Response To Stimulus Phototransduction, Visible Light Retinoid Metabolic Process Tetrapyrrole Metabolic Process Vitamin D Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Regulation Of Blood Coagulation Response To Lipid Positive Regulation Of Cholesterol Efflux Reverse Cholesterol Transport Detection Of Light Stimulus Positive Regulation Of Cholesterol Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis System Development Isoprenoid Metabolic Process Small Molecule Metabolic Process Regulation Of Cholesterol Efflux Response To Hormone Regulation Of Wound Healing Organ Development Response To Light Stimulus Vesicle-mediated Transport Receptor-mediated Endocytosis Endocytosis Regulation Of Cellular Localization Response To Organic Substance Response To Wounding Response To Abiotic Stimulus Cellular Metal Ion Homeostasis Positive Regulation Of Transport Bile Acid Metabolic Process Detection Of Abiotic Stimulus Regulation Of Cholesterol Transport Blood Coagulation Tissue Homeostasis Hemostasis Response To Nutrient Levels Heme Metabolic Process Multicellular Organismal Development
Tagcloud ?			ambulatory anabolic anthropometric calls capd catabolism causal complicating declined deterioration dialysis haemodialysis instead malnutrition mmol nutrineal nutrition osmotic peritoneal phosphates phosphorus rule solution substituted termination transferrin uraemic urea wilcoxon
Tagcloud (Difference) ?			ambulatory anabolic anthropometric calls capd catabolism causal complicating declined deterioration dialysis haemodialysis instead malnutrition mmol nutrineal nutrition osmotic peritoneal phosphates phosphorus rule solution substituted termination transferrin uraemic urea wilcoxon
Tagcloud (Intersection) ?