PFDN1 and CCDC85A

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PFDN1	CCDC85A
Gene Name		prefoldin subunit 1	coiled-coil domain containing 85A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Prefoldin Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways		Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS			Menarche (age at onset) ( 21102462)
Protein-Protein Interactions		54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235	3 interactors: NEK2 PFDN1 STMN2
Entrez ID		5201	114800
HPRD ID		05357	19098
Ensembl ID		ENSG00000113068	ENSG00000055813
Uniprot IDs		O60925	Q96PX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis	Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Centriole-centriole Cohesion Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Regulation Of Centriole-centriole Cohesion Regulation Of Mitotic Centrosome Separation Positive Regulation Of Microtubule Depolymerization Regulation Of Cytoskeleton Organization Negative Regulation Of Microtubule Polymerization Centrosome Separation Positive Regulation Of Protein Depolymerization Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Nerve Growth Factor Stimulus Regulation Of Microtubule Polymerization Positive Regulation Of Protein Complex Disassembly Regulation Of Organelle Organization Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Organization Negative Regulation Of DNA Binding Regulation Of Centrosome Cycle Negative Regulation Of Microtubule Polymerization Or Depolymerization Cytoskeleton Organization Centrosome Cycle 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Multicellular Organismal Development Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Development Regulation Of Microtubule Polymerization Or Depolymerization Cell Cycle Mitotic Sister Chromatid Segregation Regulation Of Chromosome Segregation Spindle Assembly Regulation Of DNA Binding Sister Chromatid Segregation Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Centrosome Organization Negative Regulation Of Binding Developmental Process Blastocyst Development Regulation Of Protein Depolymerization Microtubule Organizing Center Organization Cerebellum Development G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Neuron Projection Development Regulation Of Mitotic Nuclear Division Regulation Of Protein Complex Disassembly Metencephalon Development
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