PFDN1 and KIAA1377

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PFDN1	KIAA1377
Gene Name		prefoldin subunit 1	KIAA1377
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Prefoldin Complex	Cytoplasm Centrosome Midbody Ciliary Base
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly
Pathways		Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS
Protein-Protein Interactions		54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235	86 interactors: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM134A FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1D1 YWHAZ ZBED8 ZNF24
Entrez ID		5201	57562
HPRD ID		05357	17212
Ensembl ID		ENSG00000113068	ENSG00000110318
Uniprot IDs		O60925	Q9P2H0
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis	Organelle Organization Cell Cycle Mitotic Cell Cycle Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Cellular Metabolic Process Mitotic Cell Cycle Process Cellular Process Response To Light Stimulus Response To Radiation Triglyceride Catabolic Process Gene Expression Positive Regulation Of Apoptotic Signaling Pathway Organelle Localization Acylglycerol Catabolic Process Endomembrane System Organization Establishment Of Organelle Localization Cell Cycle Process Positive Regulation Of Signal Transduction Peptidyl-lysine Modification Endosome Organization Protein Localization To Organelle Positive Regulation Of Metabolic Process Anatomical Structure Development System Development Regulation Of Signal Transduction Termination Of RNA Polymerase II Transcription Cytoplasmic Transport Programmed Cell Death Chromosome Organization Cell Division Ribosomal Subunit Export From Nucleus Cell Death Regulation Of Signaling Cellular Response To Stimulus Death Histone H3 Acetylation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Ubiquitination Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Response To Abiotic Stimulus Positive Regulation Of Striated Muscle Contraction Cellular Response To Organic Substance RNA Metabolic Process Organ Development Neurotransmitter Uptake
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