SHQ1 and DKC1

Number of citations of the paper that reports this interaction (PMID 22085966)
5

Data Source:
BioGRID (pull down)

		SHQ1	DKC1
Gene Name		SHQ1, H/ACA ribonucleoprotein assembly factor	dyskeratosis congenita 1, dyskerin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body	Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytoplasm Cajal Body
	Molecular Function	Protein Binding	Telomerase Activity RNA Binding Protein Binding Pseudouridine Synthase Activity Poly(A) RNA Binding
	Biological Process	Ribonucleoprotein Complex Assembly Positive Regulation Of Apoptotic Process Negative Regulation Of RRNA Processing	Telomere Maintenance Pseudouridine Synthesis RRNA Processing RNA Processing Telomere Maintenance Via Telomerase Cell Proliferation
Pathways			Telomere Maintenance Chromosome Maintenance Extension of Telomeres Telomere Extension By Telomerase
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: DKC1 GMCL1 GMCL1P1	10 interactors: CSNK2A1 EEF1G EIF3F ERG LYPLA2 MAPK6 RUVBL1 SHQ1 SSR1 TERC
Entrez ID		55164	1736
HPRD ID		07682	02129
Ensembl ID		ENSG00000144736	ENSG00000130826
Uniprot IDs		B4DL05 Q6PI26	O60832
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Via Telomerase Spermatogenesis Male Gamete Generation Gamete Generation RNA-dependent DNA Replication Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Telomere Maintenance Via Telomere Lengthening Pseudouridine Synthesis Reproduction Single Organism Reproductive Process	Cellular Protein Metabolic Process Negative Regulation Of Potassium Ion Export Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of RRNA Processing Regulation Of Heart Rate By Hormone Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Ribosome Biogenesis Translation Ribonucleoprotein Complex Assembly
Tagcloud ?		3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized trp53 trp53loxp unmet validation	aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert
Tagcloud (Difference) ?		3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized trp53 trp53loxp unmet validation	aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert
Tagcloud (Intersection) ?