DKC1 and SHQ1

Number of citations of the paper that reports this interaction (PMID 22085966)
5

Data Source:
BioGRID (pull down)

		DKC1	SHQ1
Gene Name		dyskeratosis congenita 1, dyskerin	SHQ1, H/ACA ribonucleoprotein assembly factor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytoplasm Cajal Body	Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body
	Molecular Function	Telomerase Activity RNA Binding Protein Binding Pseudouridine Synthase Activity Poly(A) RNA Binding	Protein Binding
	Biological Process	Telomere Maintenance Pseudouridine Synthesis RRNA Processing RNA Processing Telomere Maintenance Via Telomerase Cell Proliferation	Ribonucleoprotein Complex Assembly Positive Regulation Of Apoptotic Process Negative Regulation Of RRNA Processing
Pathways		Telomere Maintenance Chromosome Maintenance Extension of Telomeres Telomere Extension By Telomerase
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CSNK2A1 EEF1G EIF3F ERG LYPLA2 MAPK6 RUVBL1 SHQ1 SSR1 TERC	3 interactors: DKC1 GMCL1 GMCL1P1
Entrez ID		1736	55164
HPRD ID		02129	07682
Ensembl ID		ENSG00000130826	ENSG00000144736
Uniprot IDs		O60832	B4DL05 Q6PI26
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Protein Metabolic Process Negative Regulation Of Potassium Ion Export Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of RRNA Processing Regulation Of Heart Rate By Hormone Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Ribosome Biogenesis Translation Ribonucleoprotein Complex Assembly	Telomere Maintenance Via Telomerase Spermatogenesis Male Gamete Generation Gamete Generation RNA-dependent DNA Replication Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Telomere Maintenance Via Telomere Lengthening Pseudouridine Synthesis Reproduction Single Organism Reproductive Process
Tagcloud ?		aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert	3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized trp53 trp53loxp unmet validation
Tagcloud (Difference) ?		aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert	3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized trp53 trp53loxp unmet validation
Tagcloud (Intersection) ?