DKC1 and ERG

Number of citations of the paper that reports this interaction (PMID 24591637)
2

Data Source:
BioGRID (pull down)

		DKC1	ERG
Gene Name		dyskeratosis congenita 1, dyskerin	v-ets avian erythroblastosis virus E26 oncogene homolog
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytoplasm Cajal Body	Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Telomerase Activity RNA Binding Protein Binding Pseudouridine Synthase Activity Poly(A) RNA Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Signal Transducer Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Telomere Maintenance Pseudouridine Synthesis RRNA Processing RNA Processing Telomere Maintenance Via Telomerase Cell Proliferation	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Signal Transduction Multicellular Organismal Development Cell Proliferation Cell Differentiation
Pathways		Telomere Maintenance Chromosome Maintenance Extension of Telomeres Telomere Extension By Telomerase
Drugs
Diseases
GWAS			Metabolite levels (HVA) ( 23319000) Neonatal lupus ( 20662065) White blood cell types ( 21738478)
Protein-Protein Interactions		10 interactors: CSNK2A1 EEF1G EIF3F ERG LYPLA2 MAPK6 RUVBL1 SHQ1 SSR1 TERC	61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2
Entrez ID		1736	2078
HPRD ID		02129	01298
Ensembl ID		ENSG00000130826	ENSG00000157554
Uniprot IDs		O60832	B4DN83 B4DVX5 P11308
PDB IDs			1SXE 4IRG 4IRH 4IRI
Enriched GO Terms of Interacting Partners?		Cellular Protein Metabolic Process Negative Regulation Of Potassium Ion Export Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of RRNA Processing Regulation Of Heart Rate By Hormone Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Ribosome Biogenesis Translation Ribonucleoprotein Complex Assembly	MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Metabolic Process Osteoblast Differentiation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Protein Refolding Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribosome Biogenesis Chromosome Organization Ossification Cis Assembly Of Pre-catalytic Spliceosome DNA Metabolic Process Regulation Of MRNA Stability Cell Differentiation Rhythmic Process Developmental Process Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process MRNA Stabilization Negative Regulation Of Transcription, DNA-templated Circadian Rhythm Ribonucleoprotein Complex Assembly
Tagcloud ?		aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?		aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?