POU3F2 and GTF2B

Number of citations of the paper that reports this interaction (PMID 11029584)
10

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		POU3F2	GTF2B
Gene Name		POU class 3 homeobox 2	general transcription factor IIB
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	Core Promoter Binding Protein Binding Transcription Factor Binding Zinc Ion Binding TBP-class Protein Binding Thyroid Hormone Receptor Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Cell Proliferation Epidermis Development Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Axonogenesis Cellular Response To Organic Substance	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways			RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (interaction) ( 19023125) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: EP300 GTF2B PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP	56 interactors: ATF4 BCL3 CIITA CREBBP CTBP1 DEPDC7 DHX9 DRAP1 EP300 ESR1 ESRRA FBXO25 FOXF2 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 HMGCL HNF4A HSF1 IKZF1 JAK3 JUN KLF5 MCM2 MECP2 MYC NCOA1 NCOA3 NCOA4 NCOR1 NOLC1 NR1D2 NR2F1 NR5A1 POLR2A POLR2E POU3F2 PSMC2 PSMC5 REL RELA REST SLC22A2 SRA1 TAF11 TAF9 TBP TBPL1 TCEA2 THRA TNIP1 TRAM2 VDR YWHAE
Entrez ID		5454	2959
HPRD ID		02734	08928
Ensembl ID		ENSG00000184486	ENSG00000137947
Uniprot IDs		P20265	Q00403
PDB IDs			1C9B 1DL6 1RLY 1RO4 1TFB 1VOL 2PHG
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Neural Crest Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Neural Crest Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mesenchymal Cell Development Nitrogen Compound Metabolic Process Mesenchymal Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Nervous System Development Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Mesenchyme Development Positive Regulation Of Macromolecule Biosynthetic Process Tube Development Positive Regulation Of Gene Expression Generation Of Neurons Stem Cell Development Positive Regulation Of Cellular Biosynthetic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Neurogenesis Autonomic Nervous System Development Muscle Organ Development Regulation Of Metabolic Process Neuroepithelial Cell Differentiation Neural Crest Cell Migration Stem Cell Differentiation Central Nervous System Development Transcription Elongation From RNA Polymerase II Promoter Organ Morphogenesis	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression DNA-templated Transcription, Initiation Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Viral Transcription Response To Organic Substance Positive Regulation Of Viral Transcription Regulation Of Viral Process Cellular Response To Organic Substance Positive Regulation Of Viral Process Metabolic Process Steroid Hormone Mediated Signaling Pathway
Tagcloud ?		200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b
Tagcloud (Difference) ?		200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b
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