POU3F2 and PAX3

Number of citations of the paper that reports this interaction (PMID 11029584)
10

Data Source:
BioGRID (two hybrid)

		POU3F2	PAX3
Gene Name		POU class 3 homeobox 2	paired box 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus
	Molecular Function	RNA Polymerase II Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Cell Proliferation Epidermis Development Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Axonogenesis Cellular Response To Organic Substance	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neural Crest Cell Migration Neural Tube Closure Transcription From RNA Polymerase II Promoter Apoptotic Process Heart Development Muscle Organ Development Sensory Perception Of Sound Cell Proliferation Positive Regulation Of Cell Proliferation Organ Morphogenesis Regulation Of Somitogenesis Spinal Cord Association Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Pigmentation Neuron Fate Commitment Mammary Gland Specification
Pathways
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (interaction) ( 19023125) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443)	Facial morphology ( 22341974)
Protein-Protein Interactions		8 interactors: EP300 GTF2B PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP	15 interactors: CIB1 DAXX HDAC10 IPO13 MEOX1 MEOX2 MITF MSX1 POU3F2 RAD23B SOX10 SOX8 TAF1 TBP WWTR1
Entrez ID		5454	5077
HPRD ID		02734	09421
Ensembl ID		ENSG00000184486	ENSG00000135903
Uniprot IDs		P20265	P23760
PDB IDs			3CMY
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Neural Crest Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Neural Crest Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mesenchymal Cell Development Nitrogen Compound Metabolic Process Mesenchymal Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Nervous System Development Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Mesenchyme Development Positive Regulation Of Macromolecule Biosynthetic Process Tube Development Positive Regulation Of Gene Expression Generation Of Neurons Stem Cell Development Positive Regulation Of Cellular Biosynthetic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Neurogenesis Autonomic Nervous System Development Muscle Organ Development Regulation Of Metabolic Process Neuroepithelial Cell Differentiation Neural Crest Cell Migration Stem Cell Differentiation Central Nervous System Development Transcription Elongation From RNA Polymerase II Promoter Organ Morphogenesis	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Mesenchyme Development Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stem Cell Differentiation Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Mesenchymal Cell Differentiation Epithelium Development Tissue Development Glial Cell Differentiation Somite Specification Gliogenesis Regulation Of Cell Proliferation Oligodendrocyte Differentiation Organ Development Regulation Of Cell Differentiation Enteric Nervous System Development System Development Peripheral Nervous System Development Mesenchymal Cell Development
Tagcloud ?		200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b	6ped activators alveolar arms chimeric chromosomal copies cotransfected diphtheria effort exploit fkhr harbor lacks p36 pa3 pax7 plasmid plasmids prs q14 q35 rearrangements rhabdomyosarcoma sorting stably toxin transfections translocations
Tagcloud (Difference) ?		200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b	6ped activators alveolar arms chimeric chromosomal copies cotransfected diphtheria effort exploit fkhr harbor lacks p36 pa3 pax7 plasmid plasmids prs q14 q35 rearrangements rhabdomyosarcoma sorting stably toxin transfections translocations
Tagcloud (Intersection) ?