POU3F2 and SOX11

Number of citations of the paper that reports this interaction (PMID 9632656)
52

Data Source:
HPRD (in vitro)

		POU3F2	SOX11
Gene Name		POU class 3 homeobox 2	SRY (sex determining region Y)-box 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Coactivator Activity Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Translation Factor Activity, Nucleic Acid Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Cell Proliferation Epidermis Development Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Axonogenesis Cellular Response To Organic Substance	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Kidney Development Neural Tube Formation Lens Morphogenesis In Camera-type Eye Outflow Tract Morphogenesis Cardiac Ventricle Formation Noradrenergic Neuron Differentiation Transcription, DNA-templated Translation Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Glial Cell Proliferation Neural Crest Cell Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Spinal Cord Development Glial Cell Development Neuron Differentiation Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Hippo Signaling Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Ossification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Secretion Sympathetic Nervous System Development Embryonic Digestive Tract Morphogenesis Embryonic Skeletal System Morphogenesis Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Neurogenesis Hard Palate Development Soft Palate Development Limb Bud Formation Negative Regulation Of Glial Cell Proliferation Ventricular Septum Morphogenesis Lung Morphogenesis Negative Regulation Of Cell Death Neuroepithelial Cell Differentiation Eyelid Development In Camera-type Eye Somite Development Cornea Development In Camera-type Eye Closure Of Optic Fissure Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Stem Cell Proliferation Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Lens Epithelial Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (interaction) ( 19023125) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443)	Chronic kidney disease ( 20383146) Crohn's disease ( 23266558) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: EP300 GTF2B PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP	2 interactors: POU3F2 POU3F3
Entrez ID		5454	6664
HPRD ID		02734	02940
Ensembl ID		ENSG00000184486	ENSG00000176887
Uniprot IDs		P20265	P35716
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Neural Crest Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Neural Crest Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mesenchymal Cell Development Nitrogen Compound Metabolic Process Mesenchymal Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Nervous System Development Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Mesenchyme Development Positive Regulation Of Macromolecule Biosynthetic Process Tube Development Positive Regulation Of Gene Expression Generation Of Neurons Stem Cell Development Positive Regulation Of Cellular Biosynthetic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Neurogenesis Autonomic Nervous System Development Muscle Organ Development Regulation Of Metabolic Process Neuroepithelial Cell Differentiation Neural Crest Cell Migration Stem Cell Differentiation Central Nervous System Development Transcription Elongation From RNA Polymerase II Promoter Organ Morphogenesis	Forebrain Ventricular Zone Progenitor Cell Division Cell Proliferation In Forebrain Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Cell Migration Telencephalon Cell Migration Forebrain Cell Migration Neural Precursor Cell Proliferation Cerebral Cortex Development Pallium Development Metanephric Macula Densa Development Metanephric DCT Cell Differentiation Telencephalon Development Neurohypophysis Development Metanephric Thick Ascending Limb Development Cell Division Forebrain Development Metanephric Ascending Thin Limb Development Metanephric Distal Convoluted Tubule Development Metanephric Loop Of Henle Development Hypothalamus Cell Differentiation Metanephric Distal Tubule Development Cell Proliferation Loop Of Henle Development Cell Differentiation Involved In Metanephros Development Brain Development Distal Tubule Development Head Development Positive Regulation Of Cell Proliferation Cell Migration Cell Motility Metanephric Nephron Tubule Development Central Nervous System Development Astrocyte Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Hypothalamus Development Epithelium Development Metanephric Epithelium Development Locomotion Positive Regulation Of Transcription, DNA-templated Cell Differentiation Involved In Kidney Development Astrocyte Differentiation Myelination In Peripheral Nervous System Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Positive Regulation Of Macromolecule Biosynthetic Process Schwann Cell Development Positive Regulation Of Gene Expression Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Cellular Biosynthetic Process Pituitary Gland Development
Tagcloud ?		200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b	barr bcl6 blastoid ccnd1 cd10 cd20 cd5 clinicopathologic coexistence convincingly cooperate differentiating dlbcl entity epstein igh immunophenotypic mantle molecularly morphologic mum1 pitfall pleomorphic pose rearrangement rearrangements relapsed rendered thorough
Tagcloud (Difference) ?		200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b	barr bcl6 blastoid ccnd1 cd10 cd20 cd5 clinicopathologic coexistence convincingly cooperate differentiating dlbcl entity epstein igh immunophenotypic mantle molecularly morphologic mum1 pitfall pleomorphic pose rearrangement rearrangements relapsed rendered thorough
Tagcloud (Intersection) ?