GTF2B and NOLC1

Number of citations of the paper that reports this interaction (PMID 12167624)
5

Data Source:
HPRD (in vitro)

		GTF2B	NOLC1
Gene Name		general transcription factor IIB	nucleolar and coiled-body phosphoprotein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleoplasm Nucleolus Cytoplasm Cajal Body
	Molecular Function	Core Promoter Binding Protein Binding Transcription Factor Binding Zinc Ion Binding TBP-class Protein Binding Thyroid Hormone Receptor Binding	Protein Binding ATP Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process	RRNA Processing Nucleolus Organization Cell Cycle Mitotic Nuclear Division
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		56 interactors: ATF4 BCL3 CIITA CREBBP CTBP1 DEPDC7 DHX9 DRAP1 EP300 ESR1 ESRRA FBXO25 FOXF2 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 HMGCL HNF4A HSF1 IKZF1 JAK3 JUN KLF5 MCM2 MECP2 MYC NCOA1 NCOA3 NCOA4 NCOR1 NOLC1 NR1D2 NR2F1 NR5A1 POLR2A POLR2E POU3F2 PSMC2 PSMC5 REL RELA REST SLC22A2 SRA1 TAF11 TAF9 TBP TBPL1 TCEA2 THRA TNIP1 TRAM2 VDR YWHAE	13 interactors: APP CEBPB COIL CSNK2A1 CSNK2B E2F4 ERG GTF2B POLR1A PRKACA USP4 YWHAG YWHAQ
Entrez ID		2959	9221
HPRD ID		08928	03864
Ensembl ID		ENSG00000137947	ENSG00000166197
Uniprot IDs		Q00403	Q14978
PDB IDs		1C9B 1DL6 1RLY 1RO4 1TFB 1VOL 2PHG
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression DNA-templated Transcription, Initiation Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Viral Transcription Response To Organic Substance Positive Regulation Of Viral Transcription Regulation Of Viral Process Cellular Response To Organic Substance Positive Regulation Of Viral Process Metabolic Process Steroid Hormone Mediated Signaling Pathway	Regulation Of Metabolic Process Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process RNA Metabolic Process Nervous System Development Negative Regulation Of Protein Metabolic Process Cell Differentiation Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Multicellular Organismal Development Apoptotic Process Regulation Of Gene Expression Programmed Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Intrinsic Apoptotic Signaling Pathway Death Regulation Of Proteasomal Protein Catabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Chemotaxis DNA-templated Transcription, Initiation Regulation Of Cellular Protein Metabolic Process Developmental Process Positive Regulation Of Intracellular Transport System Development Positive Regulation Of Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Cardiac Conduction Regulation Of Proteolysis Regulation Of Binding Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Phase Transition Protein Phosphorylation Cell Cycle Positive Regulation Of Transport Regulation Of Protein Kinase Activity Positive Regulation Of Mitochondrion Organization Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Negative Regulation Of Catalytic Activity Regulation Of Apoptotic Process Regulation Of Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Potassium Ion Export RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
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