NEK1 and CTNNAL1

Number of citations of the paper that reports this interaction (PMID 14690447)
15

Data Source:
HPRD (two hybrid)

		NEK1	CTNNAL1
Gene Name		NIMA-related kinase 1	catenin (cadherin-associated protein), alpha-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Nucleus Cytoplasm Centrosome	Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Cadherin Binding Actin Filament Binding
	Biological Process	MAPK Cascade Activation Of MAPK Activity Cellular Response To DNA Damage Stimulus Mitotic Nuclear Division Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Cilium Assembly Cell Division	Cell Adhesion Rho Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ATRX CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 KIF3A MRE11A PPP2R5A TP53BP1 TSC2 YWHAH ZNF350	9 interactors: AKAP13 C19orf57 CALU DMD NEK1 PCGF2 RNF135 SPERT USH1C
Entrez ID		4750	8727
HPRD ID		06847	09210
Ensembl ID		ENSG00000137601	ENSG00000119326
Uniprot IDs		Q5JXL9 Q96PY6	Q9UBT7
PDB IDs		4APC 4B9D
Enriched GO Terms of Interacting Partners?		Response To Stimulus Regulation Of Cellular Component Organization Cellular Response To Stimulus Negative Regulation Of Cellular Metabolic Process Nervous System Development Regulation Of Cellular Process DNA Recombination Glucocorticoid Catabolic Process Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter Regulation Of Dendrite Morphogenesis DNA Duplex Unwinding DNA Geometric Change Double-strand Break Repair Via Homologous Recombination Recombinational Repair Generation Of Neurons DNA Modification Neurogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Dendrite Development Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Lipid Kinase Activity Cellular Response To Hydroxyurea DNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Stem Cell Homeostasis Regulation Of DNA Replication Signal Transduction Neuron Differentiation Negative Regulation Of DNA Endoreduplication Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Transport Into Plasma Membrane Raft Cell Projection Organization Double-strand Break Repair System Development Regulation Of Mitotic Recombination Plus-end-directed Vesicle Transport Along Microtubule Protein Localization To Plasma Membrane Raft Regulation Of Transcription, DNA-templated Nuclear MRNA Surveillance DNA Repair Chemotaxis Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process Cell Communication Positive Regulation Of Transcription, DNA-templated Regulation Of Endocytosis Regulation Of RNA Metabolic Process Cullin Deneddylation
Tagcloud ?		axin cdk1 crb3 dock7 dsh ezrin fip200 gadd34 gsk3 hamartin herc1 hscp immunoprecipitate melted merlin moesin nade p27kip1 p75ntr pam patj pc1 pp2ac rabaptin radixin rheb rsk1 tbc7 tuberin	architecture array became clarify claudins cldn17 cldns contradictory decades downregulated ductal efforts eighteen enormous forty invasive jam junctions luminal mentioned pard3 past surrogate ten tendency tight tj tjs zo
Tagcloud (Difference) ?		axin cdk1 crb3 dock7 dsh ezrin fip200 gadd34 gsk3 hamartin herc1 hscp immunoprecipitate melted merlin moesin nade p27kip1 p75ntr pam patj pc1 pp2ac rabaptin radixin rheb rsk1 tbc7 tuberin	architecture array became clarify claudins cldn17 cldns contradictory decades downregulated ductal efforts eighteen enormous forty invasive jam junctions luminal mentioned pard3 past surrogate ten tendency tight tj tjs zo
Tagcloud (Intersection) ?