PHOX2A and ATF6B

Number of citations of the paper that reports this interaction (PMID 10644760)
9

Data Source:
HPRD (in vitro)

		PHOX2A	ATF6B
Gene Name		paired-like homeobox 2a	activating transcription factor 6 beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin	Intracellular Nucleus Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-DNA Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Noradrenergic Neuron Differentiation Transcription, DNA-templated Somatic Motor Neuron Differentiation Oculomotor Nerve Formation Trochlear Nerve Formation Locus Ceruleus Development Midbrain Development Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Transcription From RNA Polymerase II Promoter Sympathetic Nervous System Development Dopaminergic Neuron Differentiation	Transcription, DNA-templated Signal Transduction Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23577725) Prostate cancer ( 23535732)
Protein-Protein Interactions		5 interactors: ATF6B CREBBP HAND2 JUN PRKACA	9 interactors: ATF6 CDK6 CREBZF MBTPS1 MBTPS2 NFYA NFYC PHOX2A XBP1
Entrez ID		401	1388
HPRD ID		04129	02992
Ensembl ID		ENSG00000165462	ENSG00000213676
Uniprot IDs		O14813	Q6AZW6 Q99941
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Negative Regulation Of DNA Binding Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Transcription, DNA-templated Blood Vessel Morphogenesis Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Metabolic Process Outflow Tract Morphogenesis Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Embryonic Digit Morphogenesis Blood Vessel Development Positive Regulation Of Myeloid Cell Differentiation Vasculature Development Regulation Of Endothelial Cell Proliferation Regulation Of DNA Binding Regulation Of Smoothened Signaling Pathway Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Binding Embryonic Morphogenesis Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Semaphorin-plexin Signaling Pathway Involved In Outflow Tract Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Norepinephrine Biosynthetic Process Cellular Response To Potassium Ion Starvation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Osteoblast Differentiation Immune System Process Biosynthetic Process Innate Immune Response Cell Proliferation Involved In Outflow Tract Morphogenesis Leading Edge Cell Differentiation Visceral Serous Pericardium Development Histone H3-T6 Phosphorylation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Epithelial Cell Proliferation Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Response To Endoplasmic Reticulum Stress Embryonic Limb Morphogenesis Cardiovascular System Development Transcription From RNA Polymerase II Promoter	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Positive Regulation Of Gene Expression Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Kinase Activity Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of Kinase Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Transcription, DNA-templated RNA Biosynthetic Process Membrane Protein Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of RNA Biosynthetic Process Positive Regulation Of Phosphorylation Regulation Of DNA-templated Transcription In Response To Stress Regulation Of RNA Metabolic Process Positive Regulation Of Protein Modification Process RNA Metabolic Process Positive Regulation Of Hydrolase Activity Positive Regulation Of Lactation Locus Ceruleus Development Cell Dedifferentiation Trochlear Nerve Formation Positive Regulation Of Plasma Cell Differentiation Serotonin Secretion, Neurotransmission Epithelial Cell Maturation Involved In Salivary Gland Development
Tagcloud ?		abnormally abonormally adc adenosquamous alx1 bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Difference) ?		abnormally abonormally adc adenosquamous alx1 bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Intersection) ?