ATF6B and PHOX2A

Number of citations of the paper that reports this interaction (PMID 10644760)
9

Data Source:
HPRD (in vitro)

		ATF6B	PHOX2A
Gene Name		activating transcription factor 6 beta	paired-like homeobox 2a
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-DNA Complex	Nuclear Chromatin
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Transcription, DNA-templated Signal Transduction Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress	Noradrenergic Neuron Differentiation Transcription, DNA-templated Somatic Motor Neuron Differentiation Oculomotor Nerve Formation Trochlear Nerve Formation Locus Ceruleus Development Midbrain Development Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Transcription From RNA Polymerase II Promoter Sympathetic Nervous System Development Dopaminergic Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725) Prostate cancer ( 23535732)
Protein-Protein Interactions		9 interactors: ATF6 CDK6 CREBZF MBTPS1 MBTPS2 NFYA NFYC PHOX2A XBP1	5 interactors: ATF6B CREBBP HAND2 JUN PRKACA
Entrez ID		1388	401
HPRD ID		02992	04129
Ensembl ID		ENSG00000213676	ENSG00000165462
Uniprot IDs		Q6AZW6 Q99941	O14813
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Positive Regulation Of Gene Expression Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Kinase Activity Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of Kinase Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Transcription, DNA-templated RNA Biosynthetic Process Membrane Protein Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of RNA Biosynthetic Process Positive Regulation Of Phosphorylation Regulation Of DNA-templated Transcription In Response To Stress Regulation Of RNA Metabolic Process Positive Regulation Of Protein Modification Process RNA Metabolic Process Positive Regulation Of Hydrolase Activity Positive Regulation Of Lactation Locus Ceruleus Development Cell Dedifferentiation Trochlear Nerve Formation Positive Regulation Of Plasma Cell Differentiation Serotonin Secretion, Neurotransmission Epithelial Cell Maturation Involved In Salivary Gland Development	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Negative Regulation Of DNA Binding Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Transcription, DNA-templated Blood Vessel Morphogenesis Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Metabolic Process Outflow Tract Morphogenesis Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Embryonic Digit Morphogenesis Blood Vessel Development Positive Regulation Of Myeloid Cell Differentiation Vasculature Development Regulation Of Endothelial Cell Proliferation Regulation Of DNA Binding Regulation Of Smoothened Signaling Pathway Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Binding Embryonic Morphogenesis Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Semaphorin-plexin Signaling Pathway Involved In Outflow Tract Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Norepinephrine Biosynthetic Process Cellular Response To Potassium Ion Starvation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Osteoblast Differentiation Immune System Process Biosynthetic Process Innate Immune Response Cell Proliferation Involved In Outflow Tract Morphogenesis Leading Edge Cell Differentiation Visceral Serous Pericardium Development Histone H3-T6 Phosphorylation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Epithelial Cell Proliferation Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Response To Endoplasmic Reticulum Stress Embryonic Limb Morphogenesis Cardiovascular System Development Transcription From RNA Polymerase II Promoter
Tagcloud ?			abnormally abonormally adc adenosquamous alx1 bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Difference) ?			abnormally abonormally adc adenosquamous alx1 bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Intersection) ?