RHOC and RTKN

Number of citations of the paper that reports this interaction (PMID 8662891)
83

Data Source:
HPRD (two hybrid)

		RHOC	RTKN
Gene Name		ras homolog family member C	rhotekin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Cleavage Furrow Extracellular Vesicular Exosome	Cellular_component
	Molecular Function	Signal Transducer Activity Protein Binding GTP Binding	GTPase Inhibitor Activity Protein Binding GTP Binding GTP-Rho Binding
	Biological Process	Cytokinesis Small GTPase Mediated Signal Transduction Axon Guidance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apical Junction Assembly Wound Healing, Spreading Of Cells Regulation Of Small GTPase Mediated Signal Transduction Skeletal Muscle Satellite Cell Migration	Apoptotic Process Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Catalytic Activity
Pathways		Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Axon guidance Semaphorin interactions Signaling by Rho GTPases G alpha (12/13) signalling events Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ARHGAP1 CAV1 CIT DIAPH1 FAM65B ROCK1 RTKN	10 interactors: AKAP13 APP GOPC MAP1LC3A RAC2 RHOA RHOC SMURF1 TAX1BP3 TGFBR1
Entrez ID		389	6242
HPRD ID		01322	03795
Ensembl ID		ENSG00000155366	ENSG00000114993
Uniprot IDs		P08134	Q9BST9
PDB IDs		1Z2C 2GCN 2GCO 2GCP
Enriched GO Terms of Interacting Partners?		Rho Protein Signal Transduction Ras Protein Signal Transduction Intracellular Signal Transduction Regulation Of Actin Filament-based Process Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Nitric Oxide Homeostasis Regulation Of Epithelial Cell Differentiation Regulation Of Cellular Component Movement Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Sensory Perception Of Sound Regulation Of Ion Homeostasis Cell Differentiation Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Component Organization Neuron Projection Development Regulation Of Calcium Ion Transport Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Membrane To Membrane Docking Mammary Gland Involution Protein Localization To Plasma Membrane Raft Apical Constriction Leukocyte Migration Positive Regulation Of Metalloenzyme Activity Caveola Assembly Neuron Development Apoptotic Process Regulation Of Cardiac Muscle Cell Action Potential Regulation Of The Force Of Heart Contraction By Chemical Signal Protein Localization To Microtubule Programmed Cell Death Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Dendrite Morphogenesis Cellular Response To Stimulus System Development Cell Death Death Cellular Response To Hyperoxia Cellular Response To Histamine Regulation Of Catalytic Activity Muscle Organ Development	Skeletal Muscle Satellite Cell Migration Regulation Of Signal Transduction Wound Healing Small GTPase Mediated Signal Transduction Regulation Of Signaling Response To Wounding Cell Morphogenesis Involved In Differentiation Regulation Of Small GTPase Mediated Signal Transduction Axon Guidance Cell Communication Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Cell Development Intracellular Signal Transduction Cell Morphogenesis Cellular Component Assembly Axonogenesis Neuron Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus Cell Surface Receptor Signaling Pathway Response To Transforming Growth Factor Beta Platelet Activation Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Response To Growth Factor Cellular Response To Stimulus Locomotion Neuron Projection Morphogenesis Cell Differentiation Wound Healing, Spreading Of Cells Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Activation Regulation Of Intracellular Protein Transport Signal Transduction Positive Regulation Of Cell Projection Organization Movement Of Cell Or Subcellular Component Regulation Of Protein Localization Generation Of Neurons Positive Regulation Of Cellular Component Biogenesis Neuron Projection Development Rho Protein Signal Transduction Signaling Cell Projection Morphogenesis Morphogenesis Of An Epithelial Sheet Cell Part Morphogenesis Neurogenesis Enzyme Linked Receptor Protein Signaling Pathway Apical Junction Assembly
Tagcloud ?		addiction belongs compromised cytoskeletal epilepsy glioblastoma glioma gtpase homologs inversely limiting nononcogene p21cip1 phenotypes retaining rhoa rhob scarcity spheroid stat3 trafficking tumorigenic v14 vast vesicle waf1 xenograft xenografts
Tagcloud (Difference) ?		addiction belongs compromised cytoskeletal epilepsy glioblastoma glioma gtpase homologs inversely limiting nononcogene p21cip1 phenotypes retaining rhoa rhob scarcity spheroid stat3 trafficking tumorigenic v14 vast vesicle waf1 xenograft xenografts
Tagcloud (Intersection) ?