RHOC and FAM65B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RHOC	FAM65B
Gene Name		ras homolog family member C	family with sequence similarity 65, member B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Cleavage Furrow Extracellular Vesicular Exosome	Cytoplasm Mitochondrion Cytoskeleton Filopodium Stereocilium Membrane
	Molecular Function	Signal Transducer Activity Protein Binding GTP Binding	Protein Binding
	Biological Process	Cytokinesis Small GTPase Mediated Signal Transduction Axon Guidance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apical Junction Assembly Wound Healing, Spreading Of Cells Regulation Of Small GTPase Mediated Signal Transduction Skeletal Muscle Satellite Cell Migration	Muscle Organ Development Sensory Perception Of Sound Cell Differentiation
Pathways		Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Axon guidance Semaphorin interactions Signaling by Rho GTPases G alpha (12/13) signalling events Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS			Electroencephalographic traits in alcoholism ( 22554406)
Protein-Protein Interactions		7 interactors: ARHGAP1 CAV1 CIT DIAPH1 FAM65B ROCK1 RTKN	5 interactors: MAP2K2 PER1 RHOA RHOC YWHAG
Entrez ID		389	9750
HPRD ID		01322	12881
Ensembl ID		ENSG00000155366	ENSG00000111913
Uniprot IDs		P08134	F5GX51 F5H029 Q9Y4F9
PDB IDs		1Z2C 2GCN 2GCO 2GCP
Enriched GO Terms of Interacting Partners?		Rho Protein Signal Transduction Ras Protein Signal Transduction Intracellular Signal Transduction Regulation Of Actin Filament-based Process Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Nitric Oxide Homeostasis Regulation Of Epithelial Cell Differentiation Regulation Of Cellular Component Movement Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Sensory Perception Of Sound Regulation Of Ion Homeostasis Cell Differentiation Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Component Organization Neuron Projection Development Regulation Of Calcium Ion Transport Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Membrane To Membrane Docking Mammary Gland Involution Protein Localization To Plasma Membrane Raft Apical Constriction Leukocyte Migration Positive Regulation Of Metalloenzyme Activity Caveola Assembly Neuron Development Apoptotic Process Regulation Of Cardiac Muscle Cell Action Potential Regulation Of The Force Of Heart Contraction By Chemical Signal Protein Localization To Microtubule Programmed Cell Death Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Dendrite Morphogenesis Cellular Response To Stimulus System Development Cell Death Death Cellular Response To Hyperoxia Cellular Response To Histamine Regulation Of Catalytic Activity Muscle Organ Development	Skeletal Muscle Satellite Cell Migration Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signal Transduction Wound Healing, Spreading Of Cells Positive Regulation Of Signal Transduction Regulation Of Signaling Axon Guidance Regulation Of Intracellular Transport Morphogenesis Of An Epithelial Sheet Apical Junction Assembly Generation Of Neurons Axonogenesis Neurogenesis Axon Development Regulation Of Intracellular Signal Transduction Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Small GTPase Mediated Signal Transduction Response To External Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction Neuron Projection Morphogenesis Cytokinesis Cell-cell Junction Assembly Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Response To Organonitrogen Compound Nervous System Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Organelle Organization Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Organic Substance Regulation Of Stress-activated MAPK Cascade Neuron Development Cell Junction Assembly Cell-cell Junction Organization Regulation Of Cellular Localization Signaling Cell Cycle Process Regulation Of Golgi Inheritance Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cell Morphogenesis Ras Protein Signal Transduction Cell Communication Neurotrophin Signaling Pathway Circadian Regulation Of Translation
Tagcloud ?		addiction belongs compromised cytoskeletal epilepsy glioblastoma glioma gtpase homologs inversely limiting nononcogene p21cip1 phenotypes retaining rhoa rhob scarcity spheroid stat3 trafficking tumorigenic v14 vast vesicle waf1 xenograft xenografts	ambient atmosphere attached cd41 cd44 co2 colonies doubly epitopes exceeded formerly hypoxic immuno labeled lef1 li mf12 mimic monolayers n2 niches normoxia normoxic pc3 reconstitute res sorted waxman zhang
Tagcloud (Difference) ?		addiction belongs compromised cytoskeletal epilepsy glioblastoma glioma gtpase homologs inversely limiting nononcogene p21cip1 phenotypes retaining rhoa rhob scarcity spheroid stat3 trafficking tumorigenic v14 vast vesicle waf1 xenograft xenografts	ambient atmosphere attached cd41 cd44 co2 colonies doubly epitopes exceeded formerly hypoxic immuno labeled lef1 li mf12 mimic monolayers n2 niches normoxia normoxic pc3 reconstitute res sorted waxman zhang
Tagcloud (Intersection) ?