RTKN and AKAP13

Number of citations of the paper that reports this interaction (PMID 19696020)
6

Data Source:
BioGRID (pull down)

		RTKN	AKAP13
Gene Name		rhotekin	A kinase (PRKA) anchor protein 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Nucleus Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Inhibitor Activity Protein Binding GTP Binding GTP-Rho Binding	CAMP-dependent Protein Kinase Activity Signal Transducer Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding Protein Complex Scaffold Metal Ion Binding Protein Kinase A Binding
	Biological Process	Apoptotic Process Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Catalytic Activity	Protein Phosphorylation Small GTPase Mediated Signal Transduction Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Rho GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Nuclear Export Apoptotic Signaling Pathway Regulation Of Glucocorticoid Mediated Signaling Pathway
Pathways			Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS			Central corneal thickness ( 20719862) Corneal structure ( 23291589)
Protein-Protein Interactions		10 interactors: AKAP13 APP GOPC MAP1LC3A RAC2 RHOA RHOC SMURF1 TAX1BP3 TGFBR1	20 interactors: CTNNAL1 DYT10 ESR1 ESR2 GNA12 GNAQ MAP1LC3A PPARA PRKACA PRKAR2A PRKD1 RANBP2 RHOA RTKN RXRB THRA YWHAB YWHAE YWHAG YWHAZ
Entrez ID		6242	11214
HPRD ID		03795	05253
Ensembl ID		ENSG00000114993	ENSG00000170776
Uniprot IDs		Q9BST9	B0AZU4 Q12802
PDB IDs			2DRN 2LG1
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Migration Regulation Of Signal Transduction Wound Healing Small GTPase Mediated Signal Transduction Regulation Of Signaling Response To Wounding Cell Morphogenesis Involved In Differentiation Regulation Of Small GTPase Mediated Signal Transduction Axon Guidance Cell Communication Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Cell Development Intracellular Signal Transduction Cell Morphogenesis Cellular Component Assembly Axonogenesis Neuron Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus Cell Surface Receptor Signaling Pathway Response To Transforming Growth Factor Beta Platelet Activation Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Response To Growth Factor Cellular Response To Stimulus Locomotion Neuron Projection Morphogenesis Cell Differentiation Wound Healing, Spreading Of Cells Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Activation Regulation Of Intracellular Protein Transport Signal Transduction Positive Regulation Of Cell Projection Organization Movement Of Cell Or Subcellular Component Regulation Of Protein Localization Generation Of Neurons Positive Regulation Of Cellular Component Biogenesis Neuron Projection Development Rho Protein Signal Transduction Signaling Cell Projection Morphogenesis Morphogenesis Of An Epithelial Sheet Cell Part Morphogenesis Neurogenesis Enzyme Linked Receptor Protein Signaling Pathway Apical Junction Assembly	Cell Communication Signal Transduction Cellular Response To Stimulus Cellular Response To Organic Substance Signaling Cellular Response To Hormone Stimulus Regulation Of Intracellular Transport Regulation Of Establishment Of Protein Localization Response To Stimulus Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Response To Organic Substance Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Hormone Positive Regulation Of Intracellular Transport Intracellular Signal Transduction Regulation Of Cellular Localization Hormone-mediated Signaling Pathway Positive Regulation Of Phospholipase C Activity Rho Protein Signal Transduction Positive Regulation Of Mitochondrion Organization Transcription Initiation From RNA Polymerase II Promoter Apoptotic Signaling Pathway Cellular Response To Steroid Hormone Stimulus Wound Healing Intrinsic Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Platelet Activation Apoptotic Process Cellular Response To Organic Cyclic Compound Regulation Of Signaling Programmed Cell Death Positive Regulation Of Organelle Organization Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Phospholipase Activity Response To Wounding Positive Regulation Of Lipase Activity Ras Protein Signal Transduction Blood Coagulation Cell Death Death Neurotrophin Signaling Pathway Hemostasis DNA-templated Transcription, Initiation Regulation Of Mitochondrion Organization Negative Regulation Of Kinase Activity
Tagcloud ?			anchoring assume bifunctional bundle causation chair crisis dbl deregulated dh dynamical explains gdp gef gtpase guanine helical hyperactive lbc linker mediation onco pleckstrin possessing rhoa rigid scattering seat solitary
Tagcloud (Difference) ?			anchoring assume bifunctional bundle causation chair crisis dbl deregulated dh dynamical explains gdp gef gtpase guanine helical hyperactive lbc linker mediation onco pleckstrin possessing rhoa rigid scattering seat solitary
Tagcloud (Intersection) ?