KCNA3 and KCNA2

Number of citations of the paper that reports this interaction (PMID 12944270)
11

Data Source:
HPRD (in vitro)

		KCNA3	KCNA2
Gene Name		potassium channel, voltage gated shaker related subfamily A, member 3	potassium channel, voltage gated shaker related subfamily A, member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Membrane Raft	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Cell Junction Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Presynaptic Membrane Perikaryon Axon Terminus Juxtaparanode Region Of Axon
	Molecular Function	Voltage-gated Ion Channel Activity Delayed Rectifier Potassium Channel Activity Outward Rectifier Potassium Channel Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Outward Rectifier Potassium Channel Activity
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Potassium Ion Transport Synaptic Transmission Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: BAX CD3D DLG1 DLG4 IL16 KCNA2	15 interactors: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA
Entrez ID		3738	3737
HPRD ID		15937	01443
Ensembl ID		ENSG00000177272	ENSG00000177301
Uniprot IDs		P22001 Q6P2D3	A8K1Z6 P16389
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Potential Receptor Localization To Synapse Regulation Of Ion Transport Protein Localization To Synapse Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Receptor Clustering Protein Localization To Membrane Nucleotide Phosphorylation Lymphocyte Activation Regulation Of Ion Transmembrane Transport Locomotion Leukocyte Activation Single Organismal Cell-cell Adhesion Epithelial Cell Proliferation Movement Of Cell Or Subcellular Component Viral Process Release Of Matrix Enzymes From Mitochondria Positive Regulation Of Apoptotic DNA Fragmentation B Cell Receptor Apoptotic Signaling Pathway T Cell Homeostatic Proliferation Synaptic Transmission Chemotaxis Cell Activation Optic Nerve Structural Organization B Cell Negative Selection Retinal Cell Apoptotic Process Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Receptor-mediated Signaling Pathway Cellular Component Assembly Regulation Of Nitrogen Utilization Retinal Cell Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Protein Insertion Into Mitochondrial Membrane Post-embryonic Camera-type Eye Morphogenesis Positive Regulation Of Protein Complex Assembly Membrane Organization System Development Establishment Or Maintenance Of Cell Polarity Cell Part Morphogenesis Immune System Process Regulation Of Behavior B Cell Homeostatic Proliferation	Regulation Of Ion Transmembrane Transport Regulation Of Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transport Neuron Projection Development Cell-cell Signaling Neuron Development Protein Complex Assembly Potassium Ion Transmembrane Transport Neuron Differentiation Potassium Ion Transport Cell Projection Organization Cellular Component Assembly Generation Of Neurons Neuron Projection Morphogenesis Neurogenesis Axon Guidance Regulation Of Actin Filament-based Process Cell Development Locomotion Cell Junction Assembly Positive Regulation Of Cytoskeleton Organization Signaling Cell Projection Morphogenesis Cell-cell Junction Organization Cell Part Morphogenesis Cell Communication Receptor Localization To Synapse Axonogenesis Movement Of Cell Or Subcellular Component Axon Development Regulation Of Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Chemotaxis Nervous System Development Cell Morphogenesis Actin Filament-based Process Positive Regulation Of Cellular Component Biogenesis Vocalization Behavior Positive Regulation Of Actin Filament Polymerization Monovalent Inorganic Cation Transport Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Positive Regulation Of Protein Polymerization Cell Differentiation Protein Localization To Synapse Cell Morphogenesis Involved In Differentiation Regulation Of Actin Cytoskeleton Organization Dendritic Spine Organization Regulation Of Ion Transmembrane Transporter Activity
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