KCNA2 and KCNAB1

Number of citations of the paper that reports this interaction (PMID 8636142)
28

Data Source:
HPRD (in vivo)

		KCNA2	KCNAB1
Gene Name		potassium channel, voltage gated shaker related subfamily A, member 2	potassium channel, voltage gated subfamily A regulatory beta subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Cell Junction Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Presynaptic Membrane Perikaryon Axon Terminus Juxtaparanode Region Of Axon	Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Potassium Channel Complex
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Outward Rectifier Potassium Channel Activity	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity NADPH Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Potassium Ion Transport Synaptic Transmission Learning Or Memory Oxidation-reduction Process Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways		Potassium Channels Voltage gated Potassium channels	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS			Aging traits ( 17903295)
Protein-Protein Interactions		15 interactors: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	8 interactors: APP DLG1 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1
Entrez ID		3737	7881
HPRD ID		01443	03089
Ensembl ID		ENSG00000177301	ENSG00000169282
Uniprot IDs		A8K1Z6 P16389	B7Z435 B7Z8E5 F8W6W4 Q14722
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Regulation Of Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transport Neuron Projection Development Cell-cell Signaling Neuron Development Protein Complex Assembly Potassium Ion Transmembrane Transport Neuron Differentiation Potassium Ion Transport Cell Projection Organization Cellular Component Assembly Generation Of Neurons Neuron Projection Morphogenesis Neurogenesis Axon Guidance Regulation Of Actin Filament-based Process Cell Development Locomotion Cell Junction Assembly Positive Regulation Of Cytoskeleton Organization Signaling Cell Projection Morphogenesis Cell-cell Junction Organization Cell Part Morphogenesis Cell Communication Receptor Localization To Synapse Axonogenesis Movement Of Cell Or Subcellular Component Axon Development Regulation Of Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Chemotaxis Nervous System Development Cell Morphogenesis Actin Filament-based Process Positive Regulation Of Cellular Component Biogenesis Vocalization Behavior Positive Regulation Of Actin Filament Polymerization Monovalent Inorganic Cation Transport Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Positive Regulation Of Protein Polymerization Cell Differentiation Protein Localization To Synapse Cell Morphogenesis Involved In Differentiation Regulation Of Actin Cytoskeleton Organization Dendritic Spine Organization Regulation Of Ion Transmembrane Transporter Activity	Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Regulation Of Ion Transmembrane Transport Viral Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Zinc Ion Transmembrane Transport Regulation Of Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Zinc Ion Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Metal Ion Transport Neuromuscular Junction Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Localization Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Action Potential Cation Transport Regulation Of Synapse Structure Or Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Ion Transport Immune Response Ion Transmembrane Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Optic Nerve Structural Organization Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Cell Recognition Regulation Of Ion Transmembrane Transporter Activity Collateral Sprouting In Absence Of Injury Regulation Of Transmembrane Transporter Activity Cell Activation Protein Polyubiquitination Synapse Organization Positive Regulation Of Transport Transport T Cell Cytokine Production Collateral Sprouting Axon Midline Choice Point Recognition Transmembrane Transport Regulation Of Cellular Response To Growth Factor Stimulus Ion Transport Cell Development Positive Regulation Of Ion Transport Progesterone Receptor Signaling Pathway
Tagcloud ?			430v2 affymetrix alpha1 anatomical antipsychotic clozapine coregulation developmentally dysregulation encode gated haloperidol inbred kchip3 kv kv1 kvbeta1 nedd4 neurogenesis neurotransmission olanzapine psychotic rodent shaker subfamily thirteen undertaken voltage
Tagcloud (Difference) ?			430v2 affymetrix alpha1 anatomical antipsychotic clozapine coregulation developmentally dysregulation encode gated haloperidol inbred kchip3 kv kv1 kvbeta1 nedd4 neurogenesis neurotransmission olanzapine psychotic rodent shaker subfamily thirteen undertaken voltage
Tagcloud (Intersection) ?