KCNA2 and PTPRA

Number of citations of the paper that reports this interaction (PMID 15588985)
37

Data Source:
HPRD (in vitro, in vivo)

		KCNA2	PTPRA
Gene Name		potassium channel, voltage gated shaker related subfamily A, member 2	protein tyrosine phosphatase, receptor type, A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Cell Junction Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Presynaptic Membrane Perikaryon Axon Terminus Juxtaparanode Region Of Axon	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Outward Rectifier Potassium Channel Activity	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Protein Phosphorylation Axon Guidance Insulin Receptor Signaling Pathway Peptidyl-tyrosine Dephosphorylation
Pathways		Potassium Channels Voltage gated Potassium channels	Axon guidance NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	12 interactors: BCAR1 CALM1 FYN GABARAPL2 GRB2 KCNA2 PRKCD PTPRD PTPRF PTPRM PTPRS SRC
Entrez ID		3737	5786
HPRD ID		01443	01476
Ensembl ID		ENSG00000177301	ENSG00000132670
Uniprot IDs		A8K1Z6 P16389	B7Z2A4 P18433
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Regulation Of Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transport Neuron Projection Development Cell-cell Signaling Neuron Development Protein Complex Assembly Potassium Ion Transmembrane Transport Neuron Differentiation Potassium Ion Transport Cell Projection Organization Cellular Component Assembly Generation Of Neurons Neuron Projection Morphogenesis Neurogenesis Axon Guidance Regulation Of Actin Filament-based Process Cell Development Locomotion Cell Junction Assembly Positive Regulation Of Cytoskeleton Organization Signaling Cell Projection Morphogenesis Cell-cell Junction Organization Cell Part Morphogenesis Cell Communication Receptor Localization To Synapse Axonogenesis Movement Of Cell Or Subcellular Component Axon Development Regulation Of Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Chemotaxis Nervous System Development Cell Morphogenesis Actin Filament-based Process Positive Regulation Of Cellular Component Biogenesis Vocalization Behavior Positive Regulation Of Actin Filament Polymerization Monovalent Inorganic Cation Transport Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Positive Regulation Of Protein Polymerization Cell Differentiation Protein Localization To Synapse Cell Morphogenesis Involved In Differentiation Regulation Of Actin Cytoskeleton Organization Dendritic Spine Organization Regulation Of Ion Transmembrane Transporter Activity	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Platelet Activation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Blood Coagulation Hemostasis Cell Communication Immune Response-regulating Signaling Pathway Fc Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Growth Factor Wound Healing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Response To External Stimulus Cell Adhesion Response To Wounding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Peptidyl-tyrosine Dephosphorylation Signaling Regulation Of Immune Response Nervous System Development Protein Dephosphorylation Phagocytosis T Cell Costimulation Chemotaxis Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cellular Response To Stimulus Positive Regulation Of Immune Response Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Phosphate-containing Compound Metabolic Process Cellular Response To Peptide Locomotion Response To Platelet-derived Growth Factor Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Cell Surface Receptor Signaling Pathway
Tagcloud ?			aab antigens array auc autoantibodies autoantigens bead biomarkers contain curve igg luminex microarrays nappa nondiscriminating ovarian panel probed programmable ptgfr ranging retested sensitivities sera serous spauc specificity top twelve
Tagcloud (Difference) ?			aab antigens array auc autoantibodies autoantigens bead biomarkers contain curve igg luminex microarrays nappa nondiscriminating ovarian panel probed programmable ptgfr ranging retested sensitivities sera serous spauc specificity top twelve
Tagcloud (Intersection) ?