KCNA2 and CTTN

Number of citations of the paper that reports this interaction (PMID 12151401)
18

Data Source:
HPRD (in vivo, in vitro)

		KCNA2	CTTN
Gene Name		potassium channel, voltage gated shaker related subfamily A, member 2	cortactin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Cell Junction Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Presynaptic Membrane Perikaryon Axon Terminus Juxtaparanode Region Of Axon	Ruffle Cytoplasm Cytoskeleton Actin Filament Coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Lamellipodium Growth Cone Cortical Cytoskeleton Dendritic Spine Extracellular Vesicular Exosome Mitotic Spindle Midzone
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Outward Rectifier Potassium Channel Activity	Protein Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Dendritic Spine Maintenance Lamellipodium Organization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	36 interactors: ACD ACTA1 ACTG1 ACTR2 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 MET MYLK SDC3 SHANK2 SIRT1 SPRR2A SRC SYK TINF2 TJP1 TNK2 WASL WIPF1
Entrez ID		3737	2017
HPRD ID		01443	01268
Ensembl ID		ENSG00000177301	ENSG00000085733
Uniprot IDs		A8K1Z6 P16389	Q14247 Q53HG7
PDB IDs			1X69 2D1X
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transmembrane Transport Regulation Of Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transport Neuron Projection Development Cell-cell Signaling Neuron Development Protein Complex Assembly Potassium Ion Transmembrane Transport Neuron Differentiation Potassium Ion Transport Cell Projection Organization Cellular Component Assembly Generation Of Neurons Neuron Projection Morphogenesis Neurogenesis Axon Guidance Regulation Of Actin Filament-based Process Cell Development Locomotion Cell Junction Assembly Positive Regulation Of Cytoskeleton Organization Signaling Cell Projection Morphogenesis Cell-cell Junction Organization Cell Part Morphogenesis Cell Communication Receptor Localization To Synapse Axonogenesis Movement Of Cell Or Subcellular Component Axon Development Regulation Of Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Chemotaxis Nervous System Development Cell Morphogenesis Actin Filament-based Process Positive Regulation Of Cellular Component Biogenesis Vocalization Behavior Positive Regulation Of Actin Filament Polymerization Monovalent Inorganic Cation Transport Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Positive Regulation Of Protein Polymerization Cell Differentiation Protein Localization To Synapse Cell Morphogenesis Involved In Differentiation Regulation Of Actin Cytoskeleton Organization Dendritic Spine Organization Regulation Of Ion Transmembrane Transporter Activity	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Endocytosis Fc Receptor Signaling Pathway Cellular Response To Stimulus Cellular Component Assembly Regulation Of Cellular Component Organization Actin Cytoskeleton Organization Actin Filament-based Process Anatomical Structure Development Response To External Stimulus Developmental Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Phagocytosis Cell Communication Positive Regulation Of Organelle Organization Multicellular Organismal Development Immune Response-activating Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Organelle Organization Movement Of Cell Or Subcellular Component Chemotaxis Immune Response-regulating Signaling Pathway System Development Signaling Cytoskeleton Organization Signal Transduction Positive Regulation Of Immune System Process Response To Stimulus Cell Projection Organization Cell Morphogenesis Involved In Differentiation Axon Guidance Locomotion Innate Immune Response Positive Regulation Of Protein Complex Assembly Regulation Of Immune System Process Cell Morphogenesis Actin Filament Organization Positive Regulation Of Immune Response Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Immune Response Peptidyl-tyrosine Autophosphorylation Regulation Of Protein Complex Assembly Positive Regulation Of Cytoskeleton Organization
Tagcloud ?			applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1
Tagcloud (Difference) ?			applicability csmd1 delineate emphasized fadd fgf4 fhit floor gains gata4 imbalances individualized losses mandatory mccc1 mlpa mouth mtus1 multiplex p428 panel probe probemix propensity ptk2 rarb relapses tier wisp1
Tagcloud (Intersection) ?