ITGAM and CD209

Number of citations of the paper that reports this interaction (PMID 16246332)
17

Data Source:
HPRD (in vivo)

		ITGAM	CD209
Gene Name		integrin, alpha M (complement component 3 receptor 3 subunit)	CD209 molecule
Image
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Integrin Complex External Side Of Plasma Membrane Cell Surface Extracellular Vesicular Exosome	Cytoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Opsonin Binding Glycoprotein Binding Protein Binding Heparin Binding Heparan Sulfate Proteoglycan Binding Metal Ion Binding Protein Heterodimerization Activity	Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding
	Biological Process	Toll-like Receptor Signaling Pathway Leukocyte Migration Involved In Inflammatory Response Cell Adhesion Integrin-mediated Signaling Pathway Blood Coagulation Ectodermal Cell Differentiation Microglia Development Extracellular Matrix Organization Neutrophil Chemotaxis Toll-like Receptor 4 Signaling Pathway Innate Immune Response Cellular Extravasation Activated T Cell Proliferation Leukocyte Migration	Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Regulation Of T Cell Proliferation Innate Immune Response Peptide Antigen Transport Intracellular Transport Of Virus
Pathways		Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Integrin cell surface interactions Cell surface interactions at the vascular wall Innate Immune System
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 18204446 23273568 18204098 21408207 19165918) Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
Protein-Protein Interactions		18 interactors: AUP1 C3 CD209 CFH CLEC4M ELANE FGG GP1BA HP ICAM1 ICAM2 ICAM4 IRAK1 ITGB2 JAM3 PLAUR SHARPIN THY1	7 interactors: CEACAM1 CLEC4M CLU ICAM2 ICAM3 ITGAM VAC14
Entrez ID		3684	30835
HPRD ID		00411	05241
Ensembl ID		ENSG00000169896	ENSG00000090659
Uniprot IDs		P11215	B2R907 B4E2A8 M0QZG5 M0R0P0 Q9NNX6
PDB IDs		1A8X 1BHO 1BHQ 1IDN 1IDO 1JLM 1M1U 1MF7 1N9Z 1NA5 2LKE 2LKJ 3Q3G 3QA3 4M76	1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6
Enriched GO Terms of Interacting Partners?		Single Organismal Cell-cell Adhesion Regulation Of Immune System Process Cell Adhesion Regulation Of Immune Response Extracellular Matrix Organization Extracellular Structure Organization Defense Response Virion Attachment To Host Cell Response To Stress Immune System Process Adhesion Of Symbiont To Host Immune Response Inflammatory Response Innate Immune Response Peptide Antigen Transport Positive Regulation Of Immune System Process Positive Regulation Of Immune Response Cell-matrix Adhesion Blood Coagulation Hemostasis Cell-substrate Adhesion Leukocyte Migration Regulation Of Phosphorylation Acute Inflammatory Response To Antigenic Stimulus Acute Inflammatory Response Leukocyte Migration Involved In Inflammatory Response Complement Activation, Alternative Pathway Regulation Of Inflammatory Response Regulation Of Phosphorus Metabolic Process Regulation Of Body Fluid Levels Wound Healing Regulation Of Blood Coagulation Interaction With Host Regulation Of Protein Metabolic Process Leukocyte Cell-cell Adhesion Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of NF-kappaB Transcription Factor Activity Response To Wounding Regulation Of Wound Healing Modulation By Virus Of Host Morphology Or Physiology Negative Regulation Of Endothelial Cell Apoptotic Process Viral Genome Replication Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intracellular Transport Of Virus Positive Regulation Of Intracellular Signal Transduction Fibrinolysis Protein Activation Cascade	Cell Adhesion Single Organismal Cell-cell Adhesion Regulation Of Immune Response Extracellular Matrix Organization Extracellular Structure Organization Blood Coagulation Hemostasis Regulation Of Immune System Process Positive Regulation Of Tau-protein Kinase Activity Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Glial Cell Development Regulation Of Body Fluid Levels Wound Healing Leukocyte Proliferation Integrin-mediated Signaling Pathway Microglia Development Positive Regulation Of Neurofibrillary Tangle Assembly Response To Wounding Peptide Antigen Transport Central Nervous System Myelin Maintenance Glial Cell Differentiation Innate Immune Response Regulation Of Tau-protein Kinase Activity Negative Regulation Of Protein Homooligomerization Ectodermal Cell Differentiation Leukocyte Migration Immune System Process Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Gliogenesis Virion Attachment To Host Cell Positive Regulation Of Beta-amyloid Formation Negative Regulation Of Protein Oligomerization Adhesion Of Symbiont To Host Negative Regulation Of Beta-amyloid Formation Leukocyte Cell-cell Adhesion Chaperone-mediated Protein Complex Assembly Microglial Cell Activation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Glial Cell Proliferation Response To Misfolded Protein Immune Response Regulation Of Beta-amyloid Formation Leukocyte Migration Involved In Inflammatory Response Defense Response Regulation Of Inclusion Body Assembly Reverse Cholesterol Transport Regulation Of Amyloid Precursor Protein Catabolic Process Central Nervous System Myelination
Tagcloud ?		13qter 9p acp5 cckbr cholecystokinin chro chromosomes converter eleven ends fall39 glycoprotein integrin itgbeta2 linkage mapping mu opioid oprm1 pc1 pellucida rbp3 retinol rflp rnr1 ssc swine zona zp1	accreta assure basalis cd205 cd25 cd56 cd68 cd83 cytokeratin dec205 decidua evt extravillous foxp3 immature increta infertility intrauterine iug mann maturated miscarriage originates parietalis preeclampsia treg trophoblast whitney
Tagcloud (Difference) ?		13qter 9p acp5 cckbr cholecystokinin chro chromosomes converter eleven ends fall39 glycoprotein integrin itgbeta2 linkage mapping mu opioid oprm1 pc1 pellucida rbp3 retinol rflp rnr1 ssc swine zona zp1	accreta assure basalis cd205 cd25 cd56 cd68 cd83 cytokeratin dec205 decidua evt extravillous foxp3 immature increta infertility intrauterine iug mann maturated miscarriage originates parietalis preeclampsia treg trophoblast whitney
Tagcloud (Intersection) ?