APBA1 and CNTNAP4

Number of citations of the paper that reports this interaction (PMID 12093160)
23

Data Source:
HPRD (in vitro, in vivo)

		APBA1	CNTNAP4
Gene Name		amyloid beta (A4) precursor protein-binding, family A, member 1	contactin associated protein-like 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Golgi Apparatus Plasma Membrane Synaptic Vesicle Protein Complex Perinuclear Region Of Cytoplasm	Integral Component Of Membrane Cell Junction Dendrite Presynaptic Membrane
	Molecular Function	Beta-amyloid Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding PDZ Domain Binding Protein Complex Binding
	Biological Process	In Utero Embryonic Development Protein Complex Assembly Intracellular Protein Transport Cell Adhesion Synaptic Transmission Nervous System Development Locomotory Behavior Axon Cargo Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Multicellular Organism Growth	Cell Adhesion Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Synaptic Transmission, GABAergic Regulation Of Grooming Behavior
Pathways
Drugs
Diseases
GWAS			Response to amphetamines ( 22952603) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Sphingolipid levels ( 22359512)
Protein-Protein Interactions		15 interactors: APP CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1	6 interactors: APBA1 CASK FBXO21 MACF1 MAST3 RANBP10
Entrez ID		320	85445
HPRD ID		03879	13079
Ensembl ID		ENSG00000107282	ENSG00000152910
Uniprot IDs		Q02410	Q9C0A0
PDB IDs		1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N
Enriched GO Terms of Interacting Partners?		Secretion Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Cell-cell Signaling Synaptic Transmission Establishment Of Localization In Cell Transport Cellular Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Synaptic Transmission Exocytosis Cell Adhesion Ion Transport Regulation Of Grooming Behavior Metal Ion Transport Vesicle Localization Regulation Of Peptide Hormone Secretion Regulation Of Synaptic Vesicle Priming Establishment Of Protein Localization Dicarboxylic Acid Transport Regulation Of Hormone Secretion Regulation Of Membrane Potential Behavior Regulation Of Secretion Synaptic Vesicle Transport Cation Transport Regulation Of Receptor Activity Membrane Depolarization Notch Receptor Processing Extracellular Matrix Organization Extracellular Structure Organization Protein Localization Notch Signaling Pathway Glutamate Secretion Organelle Localization Regulation Of Ion Transmembrane Transport Regulation Of Exocytosis Amino Acid Transport Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Single-organism Behavior Vesicle-mediated Transport Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Behavior Calcium Ion Import Regulation Of Synaptic Vesicle Exocytosis Regulation Of Signaling
Tagcloud ?		abpa1 cask compromised consisting cortical distinctly dysregulated glutamate hypofunction involve kif17 layer mediating microtubule mlin7 mlin7a mlin7c neurotransmission nmda nr2a nr2b overlapped pathophysiology postmortem prominent schizophrenia separate trafficking transcripts
Tagcloud (Difference) ?		abpa1 cask compromised consisting cortical distinctly dysregulated glutamate hypofunction involve kif17 layer mediating microtubule mlin7 mlin7a mlin7c neurotransmission nmda nr2a nr2b overlapped pathophysiology postmortem prominent schizophrenia separate trafficking transcripts
Tagcloud (Intersection) ?