DVL3 and STOM

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DVL3	STOM
Gene Name		dishevelled segment polarity protein 3	stomatin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Extracellular Space Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Membrane Vesicle Melanosome Membrane Raft Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protease Binding Receptor Binding Frizzled Binding Protein Binding Beta-catenin Binding Protein Heterodimerization Activity	Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Outflow Tract Septum Morphogenesis Wnt Signaling Pathway Intracellular Signal Transduction Non-canonical Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Response To Drug Positive Regulation Of JUN Kinase Activity Positive Regulation Of Transcription, DNA-templated Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Homooligomerization Regulation Of Acid-sensing Ion Channel Activity
Pathways		disassembly of the destruction complex and recruitment of AXIN to the membrane WNT mediated activation of DVL misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN degradation of DVL negative regulation of TCF-dependent signaling by DVL-interacting proteins Signaling by Wnt Signaling by WNT in cancer PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		48 interactors: ADAP1 AXIN1 BAHD1 C8orf33 CCNK CSNK1D CSNK1E CSNK2A1 CTNNB1 DAB2 DIDO1 DPPA2 DVL1 ENKD1 FAM13C KAT7 KLF3 KLHL12 LNX1 LRRK2 LY6H MARK2 MATN2 NKD1 NOL12 NXF1 PIK3CB PITX1 PLN PPM1A PPP2CA PRPF3 PSMF1 RPS10 RWDD2B SNX22 STOM SYT6 TNFAIP8L1 UTP3 VANGL1 WT1 YTHDC1 ZBTB48 ZNF264 ZNF408 ZNF512B ZNF697	9 interactors: ASIC1 ASIC2 ASIC3 DVL3 LANCL1 RPL13A RUVBL1 RUVBL2 SLC2A1
Entrez ID		1857	2040
HPRD ID		03222	00585
Ensembl ID		ENSG00000161202	ENSG00000148175
Uniprot IDs		Q92997	P27105
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Wnt Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Gene Expression RNA Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Wnt Signaling Pathway RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Signal Transduction Regulation Of Cell Morphogenesis Regulation Of Proteolysis Regulation Of Cellular Component Organization Cellular Macromolecule Biosynthetic Process Positive Regulation Of Protein Modification Process Macromolecule Biosynthetic Process Negative Regulation Of Binding Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Signaling Positive Regulation Of Transferase Activity Regulation Of Transcription, DNA-templated Regulation Of Kinase Activity Protein Complex Assembly	Sensory Perception Of Sour Taste Response To PH Sensory Perception Of Taste Cellular Response To Stimulus Histone H2A Acetylation Cellular Response To PH Response To Acidic PH Response To Abiotic Stimulus Sodium Ion Transmembrane Transport Response To Stimulus Detection Of Mechanical Stimulus Involved In Sensory Perception Sodium Ion Transport Detection Of Mechanical Stimulus Histone H4 Acetylation DNA Duplex Unwinding DNA Geometric Change Enterobactin Transport Negative Regulation Of Formation Of Translation Preinitiation Complex Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Sensory Perception Of Chemical Stimulus Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Siderophore Transport Negative Regulation Of Estrogen Receptor Binding Transcriptional Activation By Promoter-enhancer Looping Protein Acetylation Dehydroascorbic Acid Transport Monovalent Inorganic Cation Transport Non-canonical Wnt Signaling Pathway Via JNK Cascade Detection Of Abiotic Stimulus Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Process Chromatin Remodeling Xenobiotic Transport Non-canonical Wnt Signaling Pathway Via MAPK Cascade Establishment Of Protein Localization To Chromatin Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Transmembrane Transport Sensory Perception Ion Transport Cellular Response To Acidic PH Negative Regulation Of Receptor Binding Response To Mechanical Stimulus Metal Ion Transport DNA Recombination Peptidyl-lysine Modification Cation Transmembrane Transport
Tagcloud ?		achieves adaptor analogous blockade dab2 encouraging erks grb2 igfi igfir influencing insufficient links mek nonredundant pharmacologic postreceptor relied responded sensitization sensitizing sevenless shc son sos synergized tracked unselected
Tagcloud (Difference) ?		achieves adaptor analogous blockade dab2 encouraging erks grb2 igfi igfir influencing insufficient links mek nonredundant pharmacologic postreceptor relied responded sensitization sensitizing sevenless shc son sos synergized tracked unselected
Tagcloud (Intersection) ?