DAG1 and MAP2

Number of citations of the paper that reports this interaction (PMID 18341635)
3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		DAG1	MAP2
Gene Name		dystroglycan 1 (dystrophin-associated glycoprotein 1)	microtubule-associated protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Adherens Junction Focal Adhesion Cell Outer Membrane Dystrophin-associated Glycoprotein Complex Dystroglycan Complex Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium Filopodium Node Of Ranvier Sarcolemma Costamere Membrane Raft Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Nucleolus Cytoplasm Microtubule Microtubule Associated Complex Nuclear Periphery Neuronal Cell Body Dendritic Shaft
	Molecular Function	Virus Receptor Activity Dystroglycan Binding Actin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Tubulin Binding Vinculin Binding Protein Complex Binding SH2 Domain Binding Laminin-1 Binding Alpha-actinin Binding	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Membrane Protein Ectodomain Proteolysis NLS-bearing Protein Import Into Nucleus Cytoskeletal Anchoring At Plasma Membrane Response To Virus Calcium-dependent Cell-matrix Adhesion Modulation By Virus Of Host Morphology Or Physiology Nerve Maturation Myelination In Peripheral Nervous System Extracellular Matrix Organization Negative Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of MAPK Cascade Response To Peptide Hormone Negative Regulation Of Protein Kinase B Signaling Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Commissural Neuron Axon Guidance Basement Membrane Organization	Microtubule Bundle Formation Axonogenesis Central Nervous System Neuron Development Neuron Projection Development Dendrite Morphogenesis Cellular Response To Organic Substance
Pathways		ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions
Drugs			Estramustine Paclitaxel Docetaxel
Diseases
GWAS
Protein-Protein Interactions		25 interactors: AGR2 AGR3 AGRN BGN CAV1 CAV3 DMD DRP2 FYN GRB2 ITGB1 LAMA1 LAMA2 LAMA5 MAGI1 MAP2 NCK1 RAPSN SHC1 SRC TLN1 TUBA1A UTRN WWP1 WWP2	24 interactors: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A
Entrez ID		1605	4133
HPRD ID		00546	01140
Ensembl ID		ENSG00000173402	ENSG00000078018
Uniprot IDs		Q14118	P11137 Q6NYC5
PDB IDs		1EG4
Enriched GO Terms of Interacting Partners?		Locomotion Regulation Of Cell Adhesion Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Axon Development Axon Guidance Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis System Development Neuron Projection Morphogenesis Cell Projection Organization Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Multicellular Organismal Development Positive Regulation Of Cell Adhesion Neuron Projection Development Anatomical Structure Development Cell Development Chemotaxis Negative Regulation Of Peptidyl-serine Phosphorylation Neuron Development Receptor Metabolic Process Developmental Process Extracellular Matrix Organization Extracellular Structure Organization Neuron Differentiation Regulation Of Body Fluid Levels Nervous System Development Leukocyte Migration Wound Healing Cell Adhesion Cell Differentiation Generation Of Neurons Blood Coagulation Hemostasis Neurogenesis Regulation Of Phosphorylation Regulation Of Ion Transmembrane Transporter Activity Response To Wounding Muscle Organ Development Regulation Of Transmembrane Transporter Activity Negative Regulation Of Anoikis Muscle Structure Development Regulation Of Sodium Ion Transport Regulation Of Protein Phosphorylation Regulation Of Anoikis Regulation Of Phosphorus Metabolic Process Cytoskeleton Organization	Response To Peptide Hormone Response To Peptide Axon Development Response To Organonitrogen Compound Nervous System Development Cellular Component Assembly Neuron Development Response To Wounding Platelet Activation Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Neuromuscular Process Cell Projection Organization Movement Of Cell Or Subcellular Component Blood Coagulation Neuron Projection Morphogenesis Hemostasis Generation Of Neurons Response To Hormone Locomotion Neurogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Cell Development Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Cell Projection Morphogenesis Regulation Of Body Fluid Levels Response To Growth Factor Cell Part Morphogenesis Axon Guidance Chemotaxis Wound Healing Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Response To Organic Substance Transport Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Response To External Stimulus Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Peptide Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Differentiation Cytoskeleton Organization Multicellular Organismal Development
Tagcloud ?		branches compensates dag1gai dag1rga28 della dof dormancy embryo factor3 ga ga1 gai germination germination1 insensitive lethal master overlapping phytocrome pil5 repressor rga rga28 seed seeds severely surprisingly t6 unexpected	amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally
Tagcloud (Difference) ?		branches compensates dag1gai dag1rga28 della dof dormancy embryo factor3 ga ga1 gai germination germination1 insensitive lethal master overlapping phytocrome pil5 repressor rga rga28 seed seeds severely surprisingly t6 unexpected	amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally
Tagcloud (Intersection) ?