DAG1 and AGR3

Number of citations of the paper that reports this interaction (PMID 12592373)
27

Data Source:
HPRD (two hybrid)

		DAG1	AGR3
Gene Name		dystroglycan 1 (dystrophin-associated glycoprotein 1)	anterior gradient 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Adherens Junction Focal Adhesion Cell Outer Membrane Dystrophin-associated Glycoprotein Complex Dystroglycan Complex Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium Filopodium Node Of Ranvier Sarcolemma Costamere Membrane Raft Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Extracellular Region
	Molecular Function	Virus Receptor Activity Dystroglycan Binding Actin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Tubulin Binding Vinculin Binding Protein Complex Binding SH2 Domain Binding Laminin-1 Binding Alpha-actinin Binding	Dystroglycan Binding Protein Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Membrane Protein Ectodomain Proteolysis NLS-bearing Protein Import Into Nucleus Cytoskeletal Anchoring At Plasma Membrane Response To Virus Calcium-dependent Cell-matrix Adhesion Modulation By Virus Of Host Morphology Or Physiology Nerve Maturation Myelination In Peripheral Nervous System Extracellular Matrix Organization Negative Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of MAPK Cascade Response To Peptide Hormone Negative Regulation Of Protein Kinase B Signaling Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Commissural Neuron Axon Guidance Basement Membrane Organization	Biological_process
Pathways		ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS			Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Protein-Protein Interactions		25 interactors: AGR2 AGR3 AGRN BGN CAV1 CAV3 DMD DRP2 FYN GRB2 ITGB1 LAMA1 LAMA2 LAMA5 MAGI1 MAP2 NCK1 RAPSN SHC1 SRC TLN1 TUBA1A UTRN WWP1 WWP2	7 interactors: ASB10 DAG1 ERLIN1 LYPD3 NUP62 SGTA UBQLN1
Entrez ID		1605	155465
HPRD ID		00546	16545
Ensembl ID		ENSG00000173402	ENSG00000173467
Uniprot IDs		Q14118	Q8TD06
PDB IDs		1EG4	3PH9
Enriched GO Terms of Interacting Partners?		Locomotion Regulation Of Cell Adhesion Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Axon Development Axon Guidance Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis System Development Neuron Projection Morphogenesis Cell Projection Organization Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Multicellular Organismal Development Positive Regulation Of Cell Adhesion Neuron Projection Development Anatomical Structure Development Cell Development Chemotaxis Negative Regulation Of Peptidyl-serine Phosphorylation Neuron Development Receptor Metabolic Process Developmental Process Extracellular Matrix Organization Extracellular Structure Organization Neuron Differentiation Regulation Of Body Fluid Levels Nervous System Development Leukocyte Migration Wound Healing Cell Adhesion Cell Differentiation Generation Of Neurons Blood Coagulation Hemostasis Neurogenesis Regulation Of Phosphorylation Regulation Of Ion Transmembrane Transporter Activity Response To Wounding Muscle Organ Development Regulation Of Transmembrane Transporter Activity Negative Regulation Of Anoikis Muscle Structure Development Regulation Of Sodium Ion Transport Regulation Of Protein Phosphorylation Regulation Of Anoikis Regulation Of Phosphorus Metabolic Process Cytoskeleton Organization	Nerve Maturation Viral Process Calcium-dependent Cell-matrix Adhesion Negative Regulation Of MAPK Cascade Cell-matrix Adhesion Viral Life Cycle Cell-substrate Adhesion
Tagcloud ?		branches compensates dag1gai dag1rga28 della dof dormancy embryo factor3 ga ga1 gai germination germination1 insensitive lethal master overlapping phytocrome pil5 repressor rga rga28 seed seeds severely surprisingly t6 unexpected	a375 agr2 annotation attenuates engineered flippase frt furthest highlighted ingenuity labelled landscape marginal mcf7 oestrogen outlying paralogue proteome proteostasis quantitation remodelling reprogrammed reprogrammes screens signalling silac transcriptome tsg101 undefined
Tagcloud (Difference) ?		branches compensates dag1gai dag1rga28 della dof dormancy embryo factor3 ga ga1 gai germination germination1 insensitive lethal master overlapping phytocrome pil5 repressor rga rga28 seed seeds severely surprisingly t6 unexpected	a375 agr2 annotation attenuates engineered flippase frt furthest highlighted ingenuity labelled landscape marginal mcf7 oestrogen outlying paralogue proteome proteostasis quantitation remodelling reprogrammed reprogrammes screens signalling silac transcriptome tsg101 undefined
Tagcloud (Intersection) ?