COL5A1 and MAG

Number of citations of the paper that reports this interaction (PMID 2446864)
8

Data Source:
BioGRID (pull down)

		COL5A1	MAG
Gene Name		collagen, type V, alpha 1	myelin associated glycoprotein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type V Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane Paranode Region Of Axon Schmidt-Lanterman Incisure
	Molecular Function	Integrin Binding Extracellular Matrix Structural Constituent Heparin Binding Proteoglycan Binding Metal Ion Binding Platelet-derived Growth Factor Binding	Carbohydrate Binding
	Biological Process	Blood Vessel Development Heart Morphogenesis Cell Adhesion Axon Guidance Cell Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Fibril Organization Collagen Catabolic Process Collagen Biosynthetic Process Wound Healing, Spreading Of Epidermal Cells Tendon Development Extracellular Fibril Organization Skin Development Integrin Biosynthetic Process Eye Morphogenesis Regulation Of Cellular Component Organization Negative Regulation Of Endodermal Cell Differentiation	Cell Adhesion Blood Coagulation Substantia Nigra Development Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Leukocyte Migration
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Syndecan interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth	Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Central corneal thickness ( 22814818 23493294 20719862) Corneal structure ( 23291589) Crohn's disease (need for surgery) ( 23665963) Longevity ( 20834067)
Protein-Protein Interactions		10 interactors: BMP1 COL5A3 DCN LGALS3BP MAG PDGFA PDGFB SDC3 SPARC THBS1	18 interactors: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R
Entrez ID		1289	4099
HPRD ID		00368	01160
Ensembl ID		ENSG00000130635	ENSG00000105695
Uniprot IDs		B2ZZ86 P20908 Q59EE7	P20916 Q53ES7
PDB IDs		1A89 1A9A
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Platelet Degranulation Wound Healing Response To Wounding Negative Regulation Of Phosphatidylinositol Biosynthetic Process Blood Coagulation Positive Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Hemostasis Negative Regulation Of Phospholipid Biosynthetic Process Platelet Activation Response To External Stimulus Positive Regulation Of Endothelial Cell Migration Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Platelet-derived Growth Factor Receptor-beta Signaling Pathway Response To Growth Factor Organ Development Positive Regulation Of Epithelial Cell Migration Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cell Migration Extracellular Matrix Disassembly Positive Regulation Of Cell Motility Exocytosis Regulation Of Blood Coagulation Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Endothelial Cell Migration Response To Lipid Positive Regulation Of Protein Autophosphorylation Regulation Of Wound Healing Negative Regulation Of Platelet Activation Regulation Of Epithelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Organ Morphogenesis System Development Response To Steroid Hormone Secretion By Cell Regulation Of Protein Autophosphorylation Regulation Of Cell Migration Regulation Of Platelet Activation Negative Regulation Of Endothelial Cell Proliferation Multicellular Organismal Development Positive Regulation Of MAP Kinase Activity Locomotion Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cell Motility Secretion	Axon Development Cell Morphogenesis Involved In Differentiation Axonogenesis Extracellular Matrix Disassembly Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Generation Of Neurons Collagen Catabolic Process Neuron Projection Morphogenesis Neurogenesis Neuron Development Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Cell Morphogenesis Multicellular Organismal Metabolic Process Axon Guidance Neuron Differentiation Cell Projection Morphogenesis Cell Projection Organization Cell Part Morphogenesis Nervous System Development Cell Development Extracellular Matrix Organization Extracellular Structure Organization Movement Of Cell Or Subcellular Component Cell Differentiation Chemotaxis Locomotion Anatomical Structure Morphogenesis System Development Multicellular Organismal Development Anatomical Structure Development Response To External Stimulus Developmental Process Regulation Of Cell Development Regulation Of Neurogenesis Regulation Of Cell Morphogenesis Regulation Of Cell Differentiation Regulation Of Neuron Differentiation Regulation Of Axonogenesis Cellular Response To Amino Acid Stimulus Collagen Fibril Organization Organ Development Response To Stimulus Regulation Of Neuron Projection Development Central Nervous System Development Platelet Activation Regulation Of Cell Projection Organization Head Development Tissue Development
Tagcloud ?		acan adamts5 aggrecan ameliorates articular chondrogenic degradative erosion fibrogenic fluorotagged ha hyaluronan joints macroscopically meniscal meniscus mmp13 oa periarticular safranin subchondral synovium tgfbeta1 treadmill ttr	abstract anhydrase bilayer brains carbonic cnpase coated compact concentrated edema enriched enrichment fractions gray matter myelin paranodal periaxolemmal plasmolipin prompted sevenfold tet tin triethyl vesicle vesicles virtually wmcv wmcvs
Tagcloud (Difference) ?		acan adamts5 aggrecan ameliorates articular chondrogenic degradative erosion fibrogenic fluorotagged ha hyaluronan joints macroscopically meniscal meniscus mmp13 oa periarticular safranin subchondral synovium tgfbeta1 treadmill ttr	abstract anhydrase bilayer brains carbonic cnpase coated compact concentrated edema enriched enrichment fractions gray matter myelin paranodal periaxolemmal plasmolipin prompted sevenfold tet tin triethyl vesicle vesicles virtually wmcv wmcvs
Tagcloud (Intersection) ?