USP13 and FUNDC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	FUNDC2
Description		ubiquitin specific peptidase 13	FUN14 domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Mitochondrion Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Autophagy Of Mitochondrion
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: AMFR BAG6 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A PTEN S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	11 interacting genes: ARL15 ASCC2 ATP13A2 EIF6 NACA NSF NUDT21 RGS1 SAT1 TP53I3 USP13
Entrez ID		8975	65991
HPRD ID		04666	06586
Ensembl ID		ENSG00000058056	ENSG00000165775
Uniprot IDs		A0A0A6YZ17 Q92995	Q9BWH2
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?
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