USP13 and TRA2B

		USP13	TRA2B
Description		ubiquitin specific peptidase 13	transformer 2 beta homolog
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Cell Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Glucose Stimulus Embryonic Brain Development
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		23 interacting genes: AMFR BAG6 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A PTEN S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	28 interacting genes: CDK6 CLK1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 USP13 YTHDC1 YWHAG YWHAZ ZRANB2
Entrez ID		8975	6434
HPRD ID		04666	04097
Ensembl ID		ENSG00000058056	ENSG00000136527
Uniprot IDs		A0A0A6YZ17 Q92995	P62995
PDB IDs		2L80 2LBC	2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?