USP13 and SYCP2

		USP13	SYCP2
Description		ubiquitin specific peptidase 13	synaptonemal complex protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Condensed Nuclear Chromosome, Centromeric Region Synaptonemal Complex Lateral Element Nucleus
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity	DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Mitotic G1 Phase Synaptonemal Complex Assembly Male Meiotic Nuclear Division Female Meiotic Nuclear Division Fertilization Negative Regulation Of Apoptotic Process Male Genitalia Morphogenesis Cell Division Meiotic Nuclear Division
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity	Meiotic synapsis
Drugs
Diseases
GWAS			Delirium ( 29631748)
Interacting Genes		23 interacting genes: AMFR BAG6 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A PTEN S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	4 interacting genes: HORMAD2 SRPK2 SYCP3 USP13
Entrez ID		8975	10388
HPRD ID		04666	06822
Ensembl ID		ENSG00000058056	ENSG00000196074
Uniprot IDs		A0A0A6YZ17 Q92995	Q9BX26
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?
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