USP13 and AMFR

Number of citations of the paper that reports this interaction (PubMedID 24424410)
21

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		USP13	AMFR
Description		ubiquitin specific peptidase 13	autocrine motility factor receptor
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Dendrite Growth Cone Protein-containing Complex Derlin-1 Retrotranslocation Complex Neuronal Cell Body Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity	Ubiquitin-protein Transferase Activity Protein Binding Protein Binding, Bridging Ubiquitin-ubiquitin Ligase Activity Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Chaperone Binding Ubiquitin Protein Ligase Activity BAT3 Complex Binding Ubiquitin-specific Protease Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Protein Polyubiquitination Protein Folding Ubiquitin-dependent Protein Catabolic Process Signal Transduction Aging Learning Or Memory Wnt Signaling Pathway Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Protein Binding Protein Autoubiquitination Protein K48-linked Ubiquitination Negative Regulation Of Canonical Wnt Signaling Pathway Endoplasmic Reticulum Mannose Trimming
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity	N-glycan trimming in the ER and Calnexin/Calreticulin cycle ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS			Breast cancer ( 29059683)
Interacting Genes		23 interacting genes: AMFR BAG6 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A PTEN S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1	28 interacting genes: BAG6 CRMP1 CSNK2A2 CYP2E1 DERL1 DHFR GPI HERPUD1 HTT KPNB1 MGRN1 SOD1 TOM1L1 TRIM25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2G1 UBE2G2 UBE2K UBE2N UBE2T UBE2W UBL4A UFD1 USP13 VCP
Entrez ID		8975	267
HPRD ID		04666	09130
Ensembl ID		ENSG00000058056	ENSG00000159461
Uniprot IDs		A0A0A6YZ17 Q92995	A0A024R6R5 Q9UKV5
PDB IDs		2L80 2LBC	2EJS 2LVN 2LVO 2LVP 2LVQ 2LXH 2LXP 3FSH 3H8K 3TIW 4G3O 4LAD
Enriched GO Terms of Interacting Partners?
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