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USP13
Description
ubiquitin specific peptidase 13
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytosol
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thiol-dependent Ubiquitinyl Hydrolase Activity
Ubiquitin Binding
Ubiquitin-like Protein Ligase Binding
Chaperone Binding
Proteasome Binding
BAT3 Complex Binding
Lys48-specific Deubiquitinase Activity
Biological Process
Regulation Of Transcription, DNA-templated
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Cell Proliferation
Regulation Of Autophagy
Protein Deubiquitination
Melanocyte Differentiation
Protein K29-linked Deubiquitination
Protein K6-linked Deubiquitination
Protein Stabilization
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Positive Regulation Of ERAD Pathway
Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways
Ub-specific processing proteases
Regulation of PTEN stability and activity
Drugs
Diseases
GWAS
Interacting Genes
23 interacting genes:
AMFR
BAG6
DVL1
FNBP1L
FUNDC2
GPR160
HSP90AA1
LAPTM5
MCL1
MDC1
MRPL20
MYO15A
PTEN
S100A9
SIAH2
SPRR2C
SYCP2
TRA2B
TRIM55
TRIM63
UBC
UBL4A
UIMC1
Entrez ID
8975
HPRD ID
04666
Ensembl ID
ENSG00000058056
Uniprot IDs
A0A0A6YZ17
Q92995
PDB IDs
2L80
2LBC
Enriched GO Terms of Interacting Partners
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