FBXL12 and MAST1

Number of citations of the paper that reports this interaction (PubMedID 21163940)
33

Data Source:
BioGRID (two hybrid)

		FBXL12	MAST1
Description		F-box and leucine rich repeat protein 12	microtubule associated serine/threonine kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol SCF Ubiquitin Ligase Complex	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Cell Cycle	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010) Monocyte count ( 27863252) Red blood cell count ( 29403010)
Interacting Genes		22 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FXYD3 LNX1 MARCHF2 MAST1 PSEN1 PSEN2 PSME3 RNF32 SHFL SMAD1 TGFBR1 UBE2D3 ZNF44 ZNF562 ZNF823	38 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1
Entrez ID		54850	22983
HPRD ID		12363	17469
Ensembl ID		ENSG00000127452	ENSG00000105613
Uniprot IDs		Q9NXK8	Q9Y2H9
PDB IDs			2M9X 3PS4
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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