FBXL12 and FXYD3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FBXL12	FXYD3
Description		F-box and leucine rich repeat protein 12	FXYD domain containing ion transport regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol SCF Ubiquitin Ligase Complex	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Cell Cycle	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)
Interacting Genes		22 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FXYD3 LNX1 MARCHF2 MAST1 PSEN1 PSEN2 PSME3 RNF32 SHFL SMAD1 TGFBR1 UBE2D3 ZNF44 ZNF562 ZNF823	8 interacting genes: CREB3 CREB3L1 FBXL12 LMNA MAPK6 NR4A1 NUDT3 SERBP1
Entrez ID		54850	5349
HPRD ID		12363	05410
Ensembl ID		ENSG00000127452	ENSG00000089356
Uniprot IDs		Q9NXK8	Q14802
PDB IDs
Enriched GO Terms of Interacting Partners?
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