MAST1 and AP1M2

Number of citations of the paper that reports this interaction (PubMedID 21163940)
33

Data Source:
BioGRID (two hybrid)

		MAST1	AP1M2
Description		microtubule associated serine/threonine kinase 1	adaptor related protein complex 1 subunit mu 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body	Golgi Membrane Cell Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding	Protein Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Protein Targeting Vesicle Targeting Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways			Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010) Monocyte count ( 27863252) Red blood cell count ( 29403010)	Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		38 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		22983	10053
HPRD ID		17469	06296
Ensembl ID		ENSG00000105613	ENSG00000129354
Uniprot IDs		Q9Y2H9	Q53GI5 Q9Y6Q5
PDB IDs		2M9X 3PS4
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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