CKAP2 and AGR2

Number of citations of the paper that reports this interaction (PubMedID 20888340)
17

Data Source:
BioGRID (two hybrid)

		CKAP2	AGR2
Description		cytoskeleton associated protein 2	anterior gradient 2, protein disulphide isomerase family member
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Cytoplasmic Microtubule Microtubule Cytoskeleton	Extracellular Space Endoplasmic Reticulum
	Molecular Function		Dystroglycan Binding Epidermal Growth Factor Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Mitotic Cytokinesis Apoptotic Process Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Response To Endoplasmic Reticulum Stress Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Digestive Tract Morphogenesis Positive Regulation Of Developmental Growth Lung Goblet Cell Differentiation Negative Regulation Of Cell Death Mucus Secretion Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of PERK-mediated Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Iron status biomarkers (ferritin levels) ( 28334935) Residual cognition ( 28441426) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes		5 interacting genes: AGR2 FBXO7 LRRK1 UBE2C YWHAG	20 interacting genes: APP BRD7 CATSPER1 CCDC90B CKAP2 CRMP1 DAG1 FABP2 GPSM2 KRT31 LYPD3 MED31 MLH1 NRIP1 NUP62CL POM121 RUVBL2 TMEM123 UBQLN1 UBQLN4
Entrez ID		26586	10551
HPRD ID		10832	05896
Ensembl ID		ENSG00000136108	ENSG00000106541
Uniprot IDs		Q8WWK9	O95994 Q4JM46
PDB IDs			2LNS 2LNT
Enriched GO Terms of Interacting Partners?
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