AGR2 and FABP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		AGR2	FABP2
Description		anterior gradient 2, protein disulphide isomerase family member	fatty acid binding protein 2
Image
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum	Cytosol
	Molecular Function	Dystroglycan Binding Epidermal Growth Factor Receptor Binding Protein Binding Identical Protein Binding	Fatty Acid Binding Protein Binding Long-chain Fatty Acid Binding
	Biological Process	Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Response To Endoplasmic Reticulum Stress Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Digestive Tract Morphogenesis Positive Regulation Of Developmental Growth Lung Goblet Cell Differentiation Negative Regulation Of Cell Death Mucus Secretion Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of PERK-mediated Unfolded Protein Response	Triglyceride Catabolic Process Intestinal Lipid Absorption
Pathways			Triglyceride catabolism
Drugs			Ibuprofen Dexibuprofen
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Iron status biomarkers (ferritin levels) ( 28334935) Residual cognition ( 28441426) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)	Blood protein levels ( 28240269)
Interacting Genes		20 interacting genes: APP BRD7 CATSPER1 CCDC90B CKAP2 CRMP1 DAG1 FABP2 GPSM2 KRT31 LYPD3 MED31 MLH1 NRIP1 NUP62CL POM121 RUVBL2 TMEM123 UBQLN1 UBQLN4	3 interacting genes: AGR2 ALDH1B1 TERF2IP
Entrez ID		10551	2169
HPRD ID		05896	00611
Ensembl ID		ENSG00000106541	ENSG00000145384
Uniprot IDs		O95994 Q4JM46	P12104
PDB IDs		2LNS 2LNT	1KZW 1KZX 2MJI 2MO5 3AKM 3IFB
Enriched GO Terms of Interacting Partners?
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