GRPEL2 and HSPA4

Number of citations of the paper that reports this interaction (PubMedID 9694873)
11

Data Source:
HPRD (in vitro)

		GRPEL2	HSPA4
Description		GrpE like 2, mitochondrial	heat shock protein family A (Hsp70) member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Mitochondrion	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding	Protein Binding ATP Binding
	Biological Process	Protein Folding Protein Import Into Mitochondrial Matrix Regulation Of Catalytic Activity	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly
Pathways		Mitochondrial protein import	Regulation of HSF1-mediated heat shock response
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Breast cancer ( 29059683) Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 30224653) Eyebrow thickness ( 26926045) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Reticulocyte fraction of red cells ( 27863252) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		1 interacting genes: HSPA4	65 interacting genes: ABCC2 AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DNAJB2 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPB1 HSPBP1 IKBKG KPNA2 KRT18 MUC1 NAA10 NFKB1 NR3C2 OLR1 PA2G4 PHLDA1 PPP1CA PRKACA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 RAP1A REL RELA SGTA SIRPA SMAD3 ST13 STUB1 SUGT1 TERT TOMM40 TRAF6 TRIM32 TTC1 UBE2L3 UBE3A
Entrez ID		134266	3308
HPRD ID		17079	09025
Ensembl ID		ENSG00000164284	ENSG00000170606
Uniprot IDs		Q8TAA5	P34932
PDB IDs
Enriched GO Terms of Interacting Partners?
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